The Possible Role of Novel Coronavirus 2019 Proteins in the Development of Drugs and Vaccines

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ESMAEILI GOUVARCHIN GHALEH HADI; KARIMI MOHAMMAD REZA; Rezayat Parisa; Bolandian Masomeh; Mirzaei Nodoushan Majid; Farzanehpour Mahdieh

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Journal: JOURNAL OF APPLIED BIOTECHNOLOGY REPORTS Year:2020 | Volume:7 | Issue:2 Page(s): 63-73

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Title

The Possible Role of Novel Coronavirus 2019 Proteins in the Development of Drugs and Vaccines

Author(s)

Keywords

COVID

19 Disease

SARS

CoV

SARS

CoV

2 Viral Proteins

Possible Antiviral Treatments

Possible Vaccine

Abstract

While the world has faced an epidemic disease resulted from severe acute respiratory syndrome coronavirus (SARS-CoV), a disease which has derived from a new coronavirus that has a high contagious power causing severe illness in some individuals that may even lead to death, no vaccine or special effective treatment has been offered yet. By noticing the genetic similarity between Middle East respiratory syndrome coronavirus (MERS) and SARS-CoV viruses with SARS-CoV-2 and especially between SARS-CoV and SARS-CoV-2, the aim of this research was to express the proteins of the SARS-CoV-2 virus including the spike (S), nucleocapsid (N) and other proteins in the virus and their function in entering host cells, virus replication and production on one hand, and developing possible drugs that are effective in treating this coronavirus infection by targeting the above-mentioned proteins. On the other hand, the researchers are looking to offer a possible vaccine to prevent infection with this virus by using the proteins of this virus.

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APA: Copy

ESMAEILI GOUVARCHIN GHALEH, HADI, KARIMI, MOHAMMAD REZA, Rezayat, Parisa, Bolandian, Masomeh, Mirzaei Nodoushan, Majid, & Farzanehpour, Mahdieh. (2020). The Possible Role of Novel Coronavirus 2019 Proteins in the Development of Drugs and Vaccines. JOURNAL OF APPLIED BIOTECHNOLOGY REPORTS, 7(2), 63-73. SID. https://sid.ir/paper/752786/en

Vancouver: Copy

ESMAEILI GOUVARCHIN GHALEH HADI, KARIMI MOHAMMAD REZA, Rezayat Parisa, Bolandian Masomeh, Mirzaei Nodoushan Majid, Farzanehpour Mahdieh. The Possible Role of Novel Coronavirus 2019 Proteins in the Development of Drugs and Vaccines. JOURNAL OF APPLIED BIOTECHNOLOGY REPORTS[Internet]. 2020;7(2):63-73. Available from: https://sid.ir/paper/752786/en

IEEE: Copy

HADI ESMAEILI GOUVARCHIN GHALEH, MOHAMMAD REZA KARIMI, Parisa Rezayat, Masomeh Bolandian, Majid Mirzaei Nodoushan, and Mahdieh Farzanehpour, “The Possible Role of Novel Coronavirus 2019 Proteins in the Development of Drugs and Vaccines,” JOURNAL OF APPLIED BIOTECHNOLOGY REPORTS, vol. 7, no. 2, pp. 63–73, 2020, [Online]. Available: https://sid.ir/paper/752786/en

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