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Information Journal Paper

Title

The Topical Eff ect of Cappariss spinosa Extract on Burn Wound Healing

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  0-0

Abstract

 Background: Skin Burn is one of the most common complications and it still is considered as a major public health issue throughout the world. Objectives: This experiment was conducted in order to study the eff ects of Capparis spinosa Leaves extract (CSLE) cream compared with silver sulfadiazine (SSD) cream to heal Burn Wounds in Rats. Methods: Diff erent parts of the plant (fruit, leaves and petals) were examined for antioxidant activity by 1, 1-diphenyl-2picrylhydrazyl (DPPH) assay and leave extract was chosen for prepaRation CSLE cream. Ninety adult male Wistar Rats were randomly divided into six groups; each group consists of 15 animals. After sedation, a metal heated in boiling water was used for type II skin Burning in 1. 5 cm diameter circle on the back of the Rats. Group one was not treated and considered as control. The Burned areas in 2-6 groups were covered twice a day with eucerin, SSD cream and CSLE cream (2. 5, 5 and 10 %), respectively. The percentage of the Burn Wound contraction and histopathological examinations on days 4, 9, and 14 were regarded as the parameters of our study. The obtained data were compared between the groups and days, statistically. Results: Our fi nding showed that 5 and 10% CSLE cream are more eff ective to decrease Burn Wound area compared with other groups. Additionally, there was no signifi cant diff erence between group 5 and 10% regarding Wound-size reduction (P < 0. 05). Therefore, 5% CSLE cream is the most eff ective for Wound Healing. Conclusions: This study indicated that Capparis spinosa Leaves extract has potential eff ect to acceleRate Wound Healing and decrease infl ammation in the treated Rats and it can be applied in the future, clinically.

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    APA: Copy

    KALANTAR, MOJTABA, GOUDARZI, MEHDI, FOROUZANDEH, HOSSEIN, SIAHPOOSH, AMIR, KHODAYAR, MOHAMMAD JAVAD, & Mahmoodi Koshkghazi, Sara. (2018). The Topical Eff ect of Cappariss spinosa Extract on Burn Wound Healing. JUNDISHAPUR JOURNAL OF NATURAL PHARMACEUTICAL PRODUCTS, 13(1), 0-0. SID. https://sid.ir/paper/753311/en

    Vancouver: Copy

    KALANTAR MOJTABA, GOUDARZI MEHDI, FOROUZANDEH HOSSEIN, SIAHPOOSH AMIR, KHODAYAR MOHAMMAD JAVAD, Mahmoodi Koshkghazi Sara. The Topical Eff ect of Cappariss spinosa Extract on Burn Wound Healing. JUNDISHAPUR JOURNAL OF NATURAL PHARMACEUTICAL PRODUCTS[Internet]. 2018;13(1):0-0. Available from: https://sid.ir/paper/753311/en

    IEEE: Copy

    MOJTABA KALANTAR, MEHDI GOUDARZI, HOSSEIN FOROUZANDEH, AMIR SIAHPOOSH, MOHAMMAD JAVAD KHODAYAR, and Sara Mahmoodi Koshkghazi, “The Topical Eff ect of Cappariss spinosa Extract on Burn Wound Healing,” JUNDISHAPUR JOURNAL OF NATURAL PHARMACEUTICAL PRODUCTS, vol. 13, no. 1, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/753311/en

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