مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

106
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

57
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

The Putative Role of Factor V Leiden and Prothrombin Mutations in Pregnancy Complications

Pages

  63-77

Abstract

 Context: Thrombophilia is an inherited or acquired predisposition in developing thrombosis. The two common Thrombophilia polymorphisms are Factor V Leiden (FVL) and factor II/ prothrombin G20210A (PT) gene Mutations which can contribute to negative pregnancy outcomes such as miscarriage, in-vitro fertilization (IVF) failure, preeclampsia, intrauterine growth restriction (IUGR), placental abruption, stillbirth, and pregnancyassociated venous thromboembolism. This review study sought to describe the effects of FVL and PT Mutations on Pregnancy Complications. Evidence Acquisition: In this review study, a comprehensive search was performed on Iranian and international databases including MEDLINE, PubMed, Scopus, Web of Sciences, Proquest and Google Scholar for articles published during 1996-2018. Out of 220 reviewed articles, 80 papers were ultimately selected. Results: According to these 80 selected papers, the possible relations of PT and FVL with recurrent pregnancy loss (RPL) have been widely evaluated. Several studies indicated higher risk of recurrent early miscarriages, implantation failure and fetal loss after IVF among women with FVL and PT Mutations. Conclusion: Observational studies have suggested the benefits of screening patients for thrombophilic polymorphisms in identification of women with higher risk of developing thromboembolic events and other related Pregnancy Complications. Based on such screening programs, prophylactic therapy can be limited to a selected group of women who truly need it.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    ABDI, FATEMEH, BEHBOODI MOGHADAM, ZAHRA, YAZDKHASTI, MANSOUREH, DAROONEH, TAYEBEH, & ROSTAMI, SAHAR. (2019). The Putative Role of Factor V Leiden and Prothrombin Mutations in Pregnancy Complications. ARCHIVES OF ADVANCES IN BIOSCIENCES (JOURNAL OF PARAMEDICAL SCIENCES), 10(2), 63-77. SID. https://sid.ir/paper/753996/en

    Vancouver: Copy

    ABDI FATEMEH, BEHBOODI MOGHADAM ZAHRA, YAZDKHASTI MANSOUREH, DAROONEH TAYEBEH, ROSTAMI SAHAR. The Putative Role of Factor V Leiden and Prothrombin Mutations in Pregnancy Complications. ARCHIVES OF ADVANCES IN BIOSCIENCES (JOURNAL OF PARAMEDICAL SCIENCES)[Internet]. 2019;10(2):63-77. Available from: https://sid.ir/paper/753996/en

    IEEE: Copy

    FATEMEH ABDI, ZAHRA BEHBOODI MOGHADAM, MANSOUREH YAZDKHASTI, TAYEBEH DAROONEH, and SAHAR ROSTAMI, “The Putative Role of Factor V Leiden and Prothrombin Mutations in Pregnancy Complications,” ARCHIVES OF ADVANCES IN BIOSCIENCES (JOURNAL OF PARAMEDICAL SCIENCES), vol. 10, no. 2, pp. 63–77, 2019, [Online]. Available: https://sid.ir/paper/753996/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button