Hypoglycemic and Hypolipidemic Activities of Aloe vera Leaf Mucilage in Alloxan-Induced Diabetic Rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Sefi Mediha; Chaabane Mariem; Rafrafi Moez; Zeghal Najiba

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Pharmaceutical and Biomedical Research Year:2019 | Volume:5 | Issue:3 Page(s): 29-34

Download Full-Text

View:

139

Download:

Cites:

Information Journal Paper

Title

Hypoglycemic and Hypolipidemic Activities of Aloe vera Leaf Mucilage in Alloxan-Induced Diabetic Rats

Author(s)

Sefi Mediha | Chaabane Mariem | Rafrafi Moez | Zeghal Najiba | Issue Writer Certificate

Keywords

Aloe vera

Diabetes Mellitus

Rats

Liver

Insulin secretion

Abstract

The present study aimed to evaluate the hypoglycemic and hypolipidemic activities of Aloe vera mucilage in alloxan-induced diabetic Rats. Adult male Wistar Rats were assigned into 4 groups (6 Rats/group), as follows: the first group (C) served as the controls. The second group of Rats (AL) received a single subcutaneous dose of alloxan at 120 mg kg-1bw. These groups received 1 mL of NaCl 9%. The third group (AL+Av) represented diabetic Rats treated with 1 mL of mucilage extracted from Aloe vera leaves. The fourth group (C+Av) corresponded to control Rats administered with 1 mL of Aloe vera mucilage. NaCl or Aloe vera mucilage were intraperitoneally injected to the Rats. Diabetic Rats exhibited significant hyperglycemia accompanied by glycosuria. We also observed a significant reduction in the Liver weight and glycogen content of the specimen. A reduced level of serum insulin was also observed among diabetic Rats. However, the levels of serum triglycerides and total cholesterol increased in alloxan-induced diabetic Rats. Aloe vera mucilage administration to diabetic Rats partially and totally corrected glycaemia and Liver glycogen content and serum insulin level, respectively. The Rats’ lipid status has also been improved. Medicinal plants, including Aloe vera, are expected to correct hyperglycemia and hyperlipidemia in diabetic patients to prevent the adverse effects of synthetic drugs.

Cites

No record.

References

Cite

APA: Copy

Sefi, Mediha, Chaabane, Mariem, Rafrafi, Moez, & Zeghal, Najiba. (2019). Hypoglycemic and Hypolipidemic Activities of Aloe vera Leaf Mucilage in Alloxan-Induced Diabetic Rats. PHARMACEUTICAL AND BIOMEDICAL RESEARCH, 5(3), 29-34. SID. https://sid.ir/paper/757036/en

Vancouver: Copy

Sefi Mediha, Chaabane Mariem, Rafrafi Moez, Zeghal Najiba. Hypoglycemic and Hypolipidemic Activities of Aloe vera Leaf Mucilage in Alloxan-Induced Diabetic Rats. PHARMACEUTICAL AND BIOMEDICAL RESEARCH[Internet]. 2019;5(3):29-34. Available from: https://sid.ir/paper/757036/en

IEEE: Copy

Mediha Sefi, Mariem Chaabane, Moez Rafrafi, and Najiba Zeghal, “Hypoglycemic and Hypolipidemic Activities of Aloe vera Leaf Mucilage in Alloxan-Induced Diabetic Rats,” PHARMACEUTICAL AND BIOMEDICAL RESEARCH, vol. 5, no. 3, pp. 29–34, 2019, [Online]. Available: https://sid.ir/paper/757036/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops