Pharmacological Treatment in Diabetes Mellitus Type 1 – Insulin and What Else?

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Otto Buczkowska Ewa; Jainta Natalia

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Journal Paper

Paper Information

Journal: International Journal of Endocrinology and Metabolism Year:2018 | Volume:16 | Issue:1 Page(s): 0-0

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Information Journal Paper

Title

Pharmacological Treatment in Diabetes Mellitus Type 1 – Insulin and What Else?

Author(s)

Otto Buczkowska Ewa | Jainta Natalia | Issue Writer Certificate

Keywords

Type 1 Diabetes

Insulin Therapy

Non-Insulin Adjunct Therapy

Metformin

SGLT2:Sodium-Glucose Co-Transporters

Amylin Analogue

Glucagon-Like Peptide 1 (GLP-1) Receptor Agonists

Dipeptidyl Peptidase-4 (DPP-4) Inhibitors

Abstract

The basis of treatment in autoimmune diabetes is Insulin Therapy; however, many clinical cases have proven that this method does not solve all problems. Trials of causal treatment including blocking the autoimmune processes and insulin-producing cells transplants were carried out. Those methods require more research to be concerned as efficient and safe ways of treatment in Type 1 Diabetes. The use of non-insulin adjunct treatment is a new trend. It has been successfully used in laboratories as well as clinical trials. Metformin is the most widely used drug, together with sodium-glucose co-transporters 2 (SGLT2) inhibitors, Amylin Analogues, glucagon-like peptide 1 (GLP-1) receptor agonists, and dipeptidyl peptidase-4 (DPP-4) inhibitors. The results of administration of these medicaments give good outcomes in patients with diabetes mellitus type 1. Most likely, in the near future, they will progressively be used in both adult and adolescent patients with Type 1 Diabetes. Further multicenter, randomized studies are required to evaluate the efficacy of treatment and long term safety of these drugs.

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APA: Copy

Otto Buczkowska, Ewa, & Jainta, Natalia. (2018). Pharmacological Treatment in Diabetes Mellitus Type 1 – Insulin and What Else?. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 16(1), 0-0. SID. https://sid.ir/paper/758086/en

Vancouver: Copy

Otto Buczkowska Ewa, Jainta Natalia. Pharmacological Treatment in Diabetes Mellitus Type 1 – Insulin and What Else?. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2018;16(1):0-0. Available from: https://sid.ir/paper/758086/en

IEEE: Copy

Ewa Otto Buczkowska, and Natalia Jainta, “Pharmacological Treatment in Diabetes Mellitus Type 1 – Insulin and What Else?,” INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 16, no. 1, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/758086/en

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