Outcome of Corneal Collagen Cross‑ Linking in Keratoconus: Introducing the Predictive Factors

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Peyman Alireza; FEIZI AWAT; GANJALIKHANI HAKEMI MAZDAK; Hosseini Nasab Fahimeh; POURAZIZI MOHSEN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Current Ophthalmology Year:2020 | Volume:32 | Issue:1 Page(s): 19-25

Download Full-Text

View:

169

Download:

132

Cites:

Information Journal Paper

Title

Outcome of Corneal Collagen Cross‑ Linking in Keratoconus: Introducing the Predictive Factors

Author(s)

Keywords

Cornea

Corneal topography

Cross‑linking reagents

Interleukin 6

Keratoconus

Treatment outcome

Tumor necrosis factor alpha

Abstract

Purpose: To evaluate the multiple pretreatment characteristics and topographic factors of Keratoconus (KC) patients and their relationship to clinical outcomes of Corneal collagen cross‑ linking (CXL). Methods: In this prospective study, 61 patients (106 eyes) with KC as candidates for CXL were included. Demographic data including age, sex, place of birth and residence, atopic constitution, family history, rubbing history, sleep apnea, and blood group were collected via a structured checklist. Complete ophthalmologic examination and tear collection to assess tear Interleukin 6 (IL-6) and Tumor necrosis factor alpha (TNF-α ) level were performed. Topometric parameters were evaluated using a rotating Scheimpflug topography device. Changes in best corrected visual acuity (BCVA) and maximum keratometry (K-max) were considered the main predicted variables. Predictive variables were analyzed by univariate and multivariate regression. Results: The use of multivariate analysis changes in K-max was significantly associated with rubbing frequency (coefficient = 0. 94, P = 0. 02), blood group (coefficient = 4. 52, P = 0. 005), pretreatment Corneal asphericity (coefficient = − 3. 99, P ≤ 0. 001), and pretreatment central Keratoconus index (CKI) (coefficient = − 55. 38, P = 0. 001). Regarding the changes in BCVA, the multivariate analysis showed a significant association with place of birth (coefficient = − 0. 08, P = 0. 03), pretreatment BCVA (coefficient = − 0. 67, P < 0. 001), pretreatment central Corneal thickness (CCT) (coefficient = − 0. 005, P = 0. 04), and pretreatment Keratoconus index (KI) (coefficient = 0. 53, P = 0. 04). Other parameters assessed in the multivariable analysis did not appear to have an individual effect on Treatment outcomes. Conclusion: Our results demonstrated that blood group, rubbing of eye, place of birth, Corneal asphericity, pretreatment BCVA, CKI, KI, and CCT were statistically associated with the outcome of KC following CXL.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

APA: Copy

Peyman, Alireza, FEIZI, AWAT, GANJALIKHANI HAKEMI, MAZDAK, Hosseini Nasab, Fahimeh, & POURAZIZI, MOHSEN. (2020). Outcome of Corneal Collagen Cross‑ Linking in Keratoconus: Introducing the Predictive Factors. JOURNAL OF CURRENT OPHTHALMOLOGY, 32(1), 19-25. SID. https://sid.ir/paper/758461/en

Vancouver: Copy

Peyman Alireza, FEIZI AWAT, GANJALIKHANI HAKEMI MAZDAK, Hosseini Nasab Fahimeh, POURAZIZI MOHSEN. Outcome of Corneal Collagen Cross‑ Linking in Keratoconus: Introducing the Predictive Factors. JOURNAL OF CURRENT OPHTHALMOLOGY[Internet]. 2020;32(1):19-25. Available from: https://sid.ir/paper/758461/en

IEEE: Copy

Alireza Peyman, AWAT FEIZI, MAZDAK GANJALIKHANI HAKEMI, Fahimeh Hosseini Nasab, and MOHSEN POURAZIZI, “Outcome of Corneal Collagen Cross‑ Linking in Keratoconus: Introducing the Predictive Factors,” JOURNAL OF CURRENT OPHTHALMOLOGY, vol. 32, no. 1, pp. 19–25, 2020, [Online]. Available: https://sid.ir/paper/758461/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops