18F-FDG PET/CT findings in a possible MELAS syndrome: A case study

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EMAMI ARDEKANI ALIREZA; HARSINI SARA; FARD ESFAHANI ARMAGHAN; Baseri Farzaneh; EFTEKHARI MOHAMMAD

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Journal: IRANIAN JOURNAL OF NUCLEAR MEDICINE Year:2019 | Volume:27 | Issue:1 (SERIAL NUMBER 52) Page(s): 57-59

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Title

18F-FDG PET/CT findings in a possible MELAS syndrome: A case study

Author(s)

Keywords

MELAS

Seizure

PET

18F-fluorodeoxyglucose

Abstract

Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a rare congenital disorder of mitochondrial DNA, presenting a wide range of clinical symptoms comprising headaches, Seizures, aphasia, hearing loss, visual defects, and hemiparesis. Herein we report a case of a previously asymptomatic 40-year-old male who presented with recurrent headache, Seizures, Wernicke’ s aphasia, and impaired visual acuity. Investigations included CT, MRI, MR venography, MR spectroscopy, and PET/CT with 18F-fluorodeoxyglucose (18F-FDG-PET) of the brain. PET imaging showed diffuse increased 18F-FDG uptake in the right hemisphere and left temporal lobe; additionally, decreased 18F-FDG uptake was observed in the left frontoparietal lobe. The patient underwent treatment by levetiracetam, co-enzyme Q10, riboflavin, L-carnitine, and lacosamide, followed by improvement of his clinical signs and symptoms indicative of partial response to the therapy.

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APA: Copy

EMAMI ARDEKANI, ALIREZA, HARSINI, SARA, FARD ESFAHANI, ARMAGHAN, Baseri, Farzaneh, & EFTEKHARI, MOHAMMAD. (2019). 18F-FDG PET/CT findings in a possible MELAS syndrome: A case study. IRANIAN JOURNAL OF NUCLEAR MEDICINE, 27(1 (SERIAL NUMBER 52)), 57-59. SID. https://sid.ir/paper/758859/en

Vancouver: Copy

EMAMI ARDEKANI ALIREZA, HARSINI SARA, FARD ESFAHANI ARMAGHAN, Baseri Farzaneh, EFTEKHARI MOHAMMAD. 18F-FDG PET/CT findings in a possible MELAS syndrome: A case study. IRANIAN JOURNAL OF NUCLEAR MEDICINE[Internet]. 2019;27(1 (SERIAL NUMBER 52)):57-59. Available from: https://sid.ir/paper/758859/en

IEEE: Copy

ALIREZA EMAMI ARDEKANI, SARA HARSINI, ARMAGHAN FARD ESFAHANI, Farzaneh Baseri, and MOHAMMAD EFTEKHARI, “18F-FDG PET/CT findings in a possible MELAS syndrome: A case study,” IRANIAN JOURNAL OF NUCLEAR MEDICINE, vol. 27, no. 1 (SERIAL NUMBER 52), pp. 57–59, 2019, [Online]. Available: https://sid.ir/paper/758859/en

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