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Information Journal Paper

Title

SCLERODRMA IN IRANIAN CHILDREN AND ADOLESCENTS REPORT OF 35 CASES

Pages

  119-124

Abstract

 Background: Scleroderma is a multisystem autoimmune connective tissue disease characterized by thickening and hardening of the skin. Methods: Over 12 years we have observed 35 patients with scleroderma in the Pediatric Unit of Rheumatology. The diagnosis was established clinically and paraclinically in all patients.Results: There was female predominance (F:M=2/5:1) (71% females, 29% males). The age of onset was 6 months to 16 years, the mean age being 10 years. Fever, fatigue, malaise were presented in 30-60%. The frequency of symptoms and signs was: nonpitting edema in 16%, hard skin in 60%, sclerosis of distal limbs in 72%, facial sclerosis in 15%, atrophy and hyper- or hypopigmentation in 40%, telangiectasis in 15%, subcutaneous calcification in 10%. RAYNAUD'S PHENOMENON in 60%, digital ulceration in 16%, muscle pain and weakness, and arthralgia in 30%. Rare manifestations included, dysphagia (16%), dyspnea (15%), cardiovascular disease, pericarditis, cardiomegaly, and CHF in 15%. Laboratory abnormalities included: anemia in 60%, positive F-ANA>1/160 (20%), ESR>50 (40%), CRP 3+ (40%). Skin biopsy documented increase in the collagen content of dermis in 75%.Conclusion: Scleroderma is not rare disease in Iranian children in compared with European children, but it is more rare in comparison with adult.

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    APA: Copy

    MORADINEZHAD, MOHAMMAD HASAN. (2005). SCLERODRMA IN IRANIAN CHILDREN AND ADOLESCENTS REPORT OF 35 CASES. IRANIAN JOURNAL OF PEDIATRICS, 15(2), 119-124. SID. https://sid.ir/paper/76131/en

    Vancouver: Copy

    MORADINEZHAD MOHAMMAD HASAN. SCLERODRMA IN IRANIAN CHILDREN AND ADOLESCENTS REPORT OF 35 CASES. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2005;15(2):119-124. Available from: https://sid.ir/paper/76131/en

    IEEE: Copy

    MOHAMMAD HASAN MORADINEZHAD, “SCLERODRMA IN IRANIAN CHILDREN AND ADOLESCENTS REPORT OF 35 CASES,” IRANIAN JOURNAL OF PEDIATRICS, vol. 15, no. 2, pp. 119–124, 2005, [Online]. Available: https://sid.ir/paper/76131/en

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