Cold Agglutinin Disease in Non-Secretory Multiple Myeloma: A Case Report

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ABBASZADEH MAHSA; Radkhah Hanieh; Karimpour Reyhan Sahar; Khajavi Rad Nasim

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Journal Paper

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Journal: Case Reports in Clinical Practice Year:2019 | Volume:4 | Issue:4 Page(s): 110-114

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Title

Cold Agglutinin Disease in Non-Secretory Multiple Myeloma: A Case Report

Author(s)

ABBASZADEH MAHSA | Radkhah Hanieh | Karimpour Reyhan Sahar | Khajavi Rad Nasim | Issue Writer Certificate

Keywords

Cold agglutinin

Multiple myeloma

Raynaud’

s phenomenon

Anemia

Abstract

Skin involvement is not common as the first manifestation of Multiple myeloma (MM). Although extremely rare, leucocytoclastic vasculitis, plasmasytoma, autoimmune bullous disease, livedo reticularis and Raynaud’; s phenomenon may be the initial presentation of MM. Raynaud’; s phenomenon and livedo reticularis related to cold exposure can be due to Cold agglutinin Disease (CAD) or cryoglobulinemia and can be seen as the first manifestation of MM. In this case study, we described a 55-year-old man complaining of limbs livedo reticularis and Raynaud’; s phenomenon during cold weather. Further evaluations revealed Anemia and elevated ESR. Skull X-ray showed multiple punched-out lesions. Finally, serum protein electrophoresis and bone marrow aspiration confirmed the diagnosis of non-secretory MM as the underlying disease of CAD. The patient was referred to the hematologist for the treatment of MM.

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APA: Copy

ABBASZADEH, MAHSA, Radkhah, Hanieh, Karimpour Reyhan, Sahar, & Khajavi Rad, Nasim. (2019). Cold Agglutinin Disease in Non-Secretory Multiple Myeloma: A Case Report. CASE REPORTS IN CLINICAL PRACTICE, 4(4), 110-114. SID. https://sid.ir/paper/761595/en

Vancouver: Copy

ABBASZADEH MAHSA, Radkhah Hanieh, Karimpour Reyhan Sahar, Khajavi Rad Nasim. Cold Agglutinin Disease in Non-Secretory Multiple Myeloma: A Case Report. CASE REPORTS IN CLINICAL PRACTICE[Internet]. 2019;4(4):110-114. Available from: https://sid.ir/paper/761595/en

IEEE: Copy

MAHSA ABBASZADEH, Hanieh Radkhah, Sahar Karimpour Reyhan, and Nasim Khajavi Rad, “Cold Agglutinin Disease in Non-Secretory Multiple Myeloma: A Case Report,” CASE REPORTS IN CLINICAL PRACTICE, vol. 4, no. 4, pp. 110–114, 2019, [Online]. Available: https://sid.ir/paper/761595/en

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