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Information Journal Paper

Title

New-Onset Diabetes Mellitus After the First Attack of Acute Pancreatitis: A Systematic Review and Meta-Analysis

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  0-0

Abstract

 Context: New-Onset Diabetes Mellitus (DM) after the first attack of Acute Pancreatitis (AP) has not been fully elucidated. Objectives: The study aimed to explore the Incidence and time-course of pancreatic endocrine insufficiency in patients with newonset prediabetes or DM after the first attack of AP. Data Sources: A comprehensive literature review was conducted by searching four major biomedical journal databases (PubMed, Embase, Cochrane Library, andWeb of Science). Study Selection: We included all prospective clinical studies that investigated the change in the metabolization of Glucose after hospital discharge following the first attack of AP. Data Extraction: After quality assessment, data were extracted according to a standard protocol. Because of between-study heterogeneity, data were analyzed by the random-effects method. Results: The inclusion criteria were met by 12 clinical studies, including 766 patients with the first attack of AP. Prediabetes and/or DM was observed in 51% (95% CI: 55% to 63%) of the patients after the first attack of AP. The pooled Incidence of prediabetes and DM after AP was 23% (95% CI: 16% to 30%) and 18% (95% CI: 11% to 26%), respectively. The risk of New-Onset prediabetes andDMsignificantly increased in 1-3 years (relative risk (RR): 4. 00 (95% CI: 1. 68-9. 53)) and 3-5 years (RR: 2. 12 (95% CI: 1. 9-3. 8)), respectively. Conclusions: New-Onset prediabetes and/orDMafter the first attack of AP developed in 51% of the patients after hospital discharge and the risk of DM increased more than two folds over three years.

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    APA: Copy

    Liu, Qiu Ping, Hu, Cun Liang, & Chen, Niwei. (2019). New-Onset Diabetes Mellitus After the First Attack of Acute Pancreatitis: A Systematic Review and Meta-Analysis. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 21(7), 0-0. SID. https://sid.ir/paper/762343/en

    Vancouver: Copy

    Liu Qiu Ping, Hu Cun Liang, Chen Niwei. New-Onset Diabetes Mellitus After the First Attack of Acute Pancreatitis: A Systematic Review and Meta-Analysis. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2019;21(7):0-0. Available from: https://sid.ir/paper/762343/en

    IEEE: Copy

    Qiu Ping Liu, Cun Liang Hu, and Niwei Chen, “New-Onset Diabetes Mellitus After the First Attack of Acute Pancreatitis: A Systematic Review and Meta-Analysis,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 21, no. 7, pp. 0–0, 2019, [Online]. Available: https://sid.ir/paper/762343/en

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