AN OVERVIEW ON RAPID DIAGNOSIS OF INVASIVE ASPERGILLOSIS BY GALACTOMANNAN ANTIGEN DETECTION

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HEDAYATI M.T.; KHODAVAISY S.; DAVARI B.; ZAMINI GH.

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Journal: SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES Year:2012 | Volume:16 | Issue:4 (SERIAL NUMBER 62) Page(s): 70-82

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Title

AN OVERVIEW ON RAPID DIAGNOSIS OF INVASIVE ASPERGILLOSIS BY GALACTOMANNAN ANTIGEN DETECTION

Author(s)

HEDAYATI M.T. | KHODAVAISY S. | DAVARI B. | ZAMINI GH. | Issue Writer Certificate

Keywords

INVASIVE ASPERGILLOSISQ2

GALACTOMANNANQ2

DIAGNOSISQ3

Abstract

INVASIVE ASPERGILLOSIS (IA) is a major cause of morbidity and mortality in severely immuno-compromised patients. Despite the advances made in diagnostic methods, accurate DIAGNOSIS of IA is not easy. At the present time, in Iran, the DIAGNOSIS is most often made based on a combination of clinical and abnormal radiologic findings, which are nonspecific, and the treatment is often given without establishing the DIAGNOSIS. Considering the invasive and progressive nature of the disease, if proper diagnostic methods are not used, control of the disease will be difficult. Therefore establishing the DIAGNOSIS of IA at an early stage by non-invasive and specific methods is necessary for early successful treatment. The detection of circulating GALACTOMANNAN (GM) antigen in serum, bronchoalveolar lavage fluid, urine, and cerebrospinal fluid and tissue has become an important method for the early DIAGNOSIS of IA. Recent data have indicated that this test has a high specify and sensitivity and is more valuable than other methods such as culture and CT scan. In general this method is non-invasive, time-saving and specific which permits early treatment of the disease and helps physicians to select the proper treatment and other clinical measures. Certainly, well designed prospective studies with systematic sampling and use of accepted definitions are required to compare the efficiency of antigen detection in different samples and population.

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APA: Copy

HEDAYATI, M.T., KHODAVAISY, S., DAVARI, B., & ZAMINI, GH.. (2012). AN OVERVIEW ON RAPID DIAGNOSIS OF INVASIVE ASPERGILLOSIS BY GALACTOMANNAN ANTIGEN DETECTION. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, 16(4 (SERIAL NUMBER 62)), 70-82. SID. https://sid.ir/paper/76266/en

Vancouver: Copy

HEDAYATI M.T., KHODAVAISY S., DAVARI B., ZAMINI GH.. AN OVERVIEW ON RAPID DIAGNOSIS OF INVASIVE ASPERGILLOSIS BY GALACTOMANNAN ANTIGEN DETECTION. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2012;16(4 (SERIAL NUMBER 62)):70-82. Available from: https://sid.ir/paper/76266/en

IEEE: Copy

M.T. HEDAYATI, S. KHODAVAISY, B. DAVARI, and GH. ZAMINI, “AN OVERVIEW ON RAPID DIAGNOSIS OF INVASIVE ASPERGILLOSIS BY GALACTOMANNAN ANTIGEN DETECTION,” SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, vol. 16, no. 4 (SERIAL NUMBER 62), pp. 70–82, 2012, [Online]. Available: https://sid.ir/paper/76266/en

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