Comparison of the Post-Caesarean Analgesic Effect of Adding Dexmedetomidine to Paracetamol and Ketorolac: A Randomized Clinical Trial

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

IMANI FARNAD; RAHIMZADEH POUPAK; FAIZ SEYED HAMID REZA; Nowruzina Shiva; SHAKERI ASADOLLAH; GHAHREMANI MOHAMMAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Anesthesiology and Pain Medicine Year:2018 | Volume:8 | Issue:5 Page(s): 0-0

Download Full-Text

View:

108

Download:

172

Cites:

Information Journal Paper

Title

Comparison of the Post-Caesarean Analgesic Effect of Adding Dexmedetomidine to Paracetamol and Ketorolac: A Randomized Clinical Trial

Author(s)

Keywords

Analgesia

Caesarean Section

Dexmedetomidine

Ketorolac

Paracetamol

Abstract

Background: Paracetamol and non-steroidal anti-inflammatory drugs (e. g. Ketorolac) can be considered for mild to moderate post-caesarean pain. As a selective α-2 agonist adrenergic receptor, Dexmedetomidine has analgesic and sedative effects without causing respiratory depression. Objectives: This study aimed to evaluate the effects of adding Dexmedetomidine to Paracetamol or Ketorolac on post-caesarean pain and the associated complications thereof. Methods: Sixty pregnant women, who were candidates for Caesarean Section with spinal anesthesia, were randomly assigned to either of two groups of 30 patients. For post-operative pain management, an intravenous patient-controlled Analgesia (PCA) device was used for 24 hours. Dexmedetomidine (3 µ g kg-1) was added to Paracetamol (35 mg kg-1) in the group DP and to Ketorolac (1 mg kg-1) in the group DK. Visual analog scale (VAS), Ramsay sedation scale, hemodynamic changes, rescue analgesic (meperidine) consumption, patient satisfaction, and possible complications were recorded at 6, 12, and 24, hours after surgery, and compared afterward. Results: The pain score was significantly lower in the DK group than in the DP group (P < 0. 05). The hemodynamics and sedation scale were similar in both groups. The total meperidine consumption was higher in the DP group, but it was not significantly different. Maternal satisfaction was greater in the DK group (P < 0. 05). Concerning complications, the two groups did not show statistically significant differences (P = 0. 4). Conclusions: The addition of Dexmedetomidine to Ketorolac, compared with its addition to Paracetamol, causes further reduction in the post-operative pain score and provides more satisfaction.

Cites

No record.

References

No record.

Cite

APA: Copy

IMANI, FARNAD, RAHIMZADEH, POUPAK, FAIZ, SEYED HAMID REZA, Nowruzina, Shiva, SHAKERI, ASADOLLAH, & GHAHREMANI, MOHAMMAD. (2018). Comparison of the Post-Caesarean Analgesic Effect of Adding Dexmedetomidine to Paracetamol and Ketorolac: A Randomized Clinical Trial. ANESTHESIOLOGY AND PAIN MEDICINE, 8(5), 0-0. SID. https://sid.ir/paper/762918/en

Vancouver: Copy

IMANI FARNAD, RAHIMZADEH POUPAK, FAIZ SEYED HAMID REZA, Nowruzina Shiva, SHAKERI ASADOLLAH, GHAHREMANI MOHAMMAD. Comparison of the Post-Caesarean Analgesic Effect of Adding Dexmedetomidine to Paracetamol and Ketorolac: A Randomized Clinical Trial. ANESTHESIOLOGY AND PAIN MEDICINE[Internet]. 2018;8(5):0-0. Available from: https://sid.ir/paper/762918/en

IEEE: Copy

FARNAD IMANI, POUPAK RAHIMZADEH, SEYED HAMID REZA FAIZ, Shiva Nowruzina, ASADOLLAH SHAKERI, and MOHAMMAD GHAHREMANI, “Comparison of the Post-Caesarean Analgesic Effect of Adding Dexmedetomidine to Paracetamol and Ketorolac: A Randomized Clinical Trial,” ANESTHESIOLOGY AND PAIN MEDICINE, vol. 8, no. 5, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/762918/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops