Evaluation of related variables on endothelial progenitor cells in first transient ischemic attack

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MEAMAR ROKHSAREH; NIKYAR HAMIDREZA; CHITSAZ AHMAD; DEHGHANI LEILA; NASRI MARYAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahrekord University of Medical Sciences Year:2019 | Volume:21 | Issue:4 Page(s): 157-162

Download Full-Text

View:

116

Download:

124

Cites:

Information Journal Paper

Title

Evaluation of related variables on endothelial progenitor cells in first transient ischemic attack

Author(s)

Keywords

Transient ischemic attack

Endothelial progenitor cell

Risk factors

Abstract

Background and aims: In a Transient ischemic attack (TIA), the activation of the Endothelial progenitor cells (EPCs) has a prominent role in the formation of collateral vessels. The aim of this study was to evaluate the role of effective variables (e. g., hypertension, diabetes, hyperlipidemia, cardiovascular diseases, a family history of cardiovascular diseases, and statin therapy on the level of EPCs in TIA. Methods: Thirty patients suffering from the first attack of TIA, without having a history of acute cerebral injury, surgery or trauma, and blood disorders were enrolled in this cross-sectional study. Then, flow cytometry was utilized to estimate the level of EPCs CD34 and CD309 and the results were evaluated based on the t test or the Mann-Whitney test. Finally, the Pearson or Spearman correlation was used to establish the relationship between the variables. The level of P < 0. 05 was considered statistically significant in this study. Results: The mean± SD number of CD309 in patients with hyperlipidemia was less than those with no hyperlipidemia (3. 35± 2. 77 vs. 5. 59± 3. 85, P = 0. 02) and diabetic patients had a significantly higher number of CD309 compared to non-diabetics (6. 14± 4. 89 vs, 3. 5± 3. 49, P = 0. 05). Conversely, the mean number of CD34 in groups with or without the studied variables was not statistically significant. The results further revealed that the average total of CD309 and CD34 was significantly lower in patients with hyperlipidemia as compared to those with no sign of hyperlipidemia (9. 44± 3. 05 vs. 6. 67± 4. 6, P = 0. 02). Using logistic regression, the intended variables demonstrated no significant effects on endothelial cells, and the relationship between age and the number of progenitor cells was not significant. Conclusion: In our study, only hyperlipidemia acted as a factor influencing the numbers of EPCs. Therefore, more studies with larger sample sizes are required to discover the role of these variables on progenitor cells in TIA.

Cites

No record.

References

Cite

APA: Copy

MEAMAR, ROKHSAREH, NIKYAR, HAMIDREZA, CHITSAZ, AHMAD, DEHGHANI, LEILA, & NASRI, MARYAM. (2019). Evaluation of related variables on endothelial progenitor cells in first transient ischemic attack. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 21(4), 157-162. SID. https://sid.ir/paper/763340/en

Vancouver: Copy

MEAMAR ROKHSAREH, NIKYAR HAMIDREZA, CHITSAZ AHMAD, DEHGHANI LEILA, NASRI MARYAM. Evaluation of related variables on endothelial progenitor cells in first transient ischemic attack. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;21(4):157-162. Available from: https://sid.ir/paper/763340/en

IEEE: Copy

ROKHSAREH MEAMAR, HAMIDREZA NIKYAR, AHMAD CHITSAZ, LEILA DEHGHANI, and MARYAM NASRI, “Evaluation of related variables on endothelial progenitor cells in first transient ischemic attack,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 21, no. 4, pp. 157–162, 2019, [Online]. Available: https://sid.ir/paper/763340/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops