Evaluation of Ficus carica Linn Fruit Extracts on Formalin Induced Pain in the Male Rat Paw

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MIRGHAZANFARI SAYID MAHDI; Aldein Alameh Hesam; PARVIZ MOHSEN; Ahmadi Basir Zahra

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Annals of Military and Health Sciences Research Year:2019 | Volume:17 | Issue:3 Page(s): 0-0

Download Full-Text

View:

157

Download:

158

Cites:

Information Journal Paper

Title

Evaluation of Ficus carica Linn Fruit Extracts on Formalin Induced Pain in the Male Rat Paw

Author(s)

MIRGHAZANFARI SAYID MAHDI | Aldein Alameh Hesam | PARVIZ MOHSEN | Ahmadi Basir Zahra | Issue Writer Certificate

Keywords

Persian Medicine

Fig (Ficus carica L.)

Inflammation

Pain

Abstract

Background: One of the most significant symptoms in many acute and chronic diseases is Pain. While many researches reveal side effects of many synthetic analgesic drugs, which are commonly used, new surveys are searching for new alternative analgesic drugs (especially by use of medicinal plants) with few side effects. Objectives: This study was designed to evaluate the analogous function of Ficus carica L. (one of the important medicinal plants in Persian Medicine) as an anti-nociceptive in allopathic medicine. Methods: Subcutaneous injection of formalin in rat paw was performed to establish the Pain. Formalin test was applied to assess the severity of Pain every 15 seconds for one hour. In two parts of this study, two different types of Ficus extract were used in intraperitoneal injections; the aqueous boiled Ficus extract (500, 1000, 2000 mg/kg) in comparison with distilled water (DW) and the petroleum ether extract (500, 1000 mg/kg) in comparison with DMSO. Results: The aqueous boiled Ficus extract showed no significant difference between control (DW) group and groups that had received extracts (P > 0. 05). While a significant difference between the petroleum ether extract (1000 mg/kg) and the DMSO group in the last five minutes of the study (P < 0. 05) was recorded. Anti-inflammatory examination of aqueous and ethanolic extract of Ficus fruit showed no anti-inflammatory effect; however, the petroleum ether extract displayed a dose-dependent (1000 mg/kg) anti-inflammatory effect even in comparison with sodium salicylate. Conclusions: According to the achieved results, it was concluded that there are no anti-nociceptive and anti-inflammatory effects of Ficus carica fruit aqueous extract on the formalin test in the male rat paw in doses mentioned above. However, there is a delayed anti-nociceptive effect dose-dependently and a dose-dependent anti-inflammatory effect of petroleum ether extract.

Cites

No record.

References

No record.

Cite

APA: Copy

MIRGHAZANFARI, SAYID MAHDI, Aldein Alameh, Hesam, PARVIZ, MOHSEN, & Ahmadi Basir, Zahra. (2019). Evaluation of Ficus carica Linn Fruit Extracts on Formalin Induced Pain in the Male Rat Paw. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, 17(3), 0-0. SID. https://sid.ir/paper/763736/en

Vancouver: Copy

MIRGHAZANFARI SAYID MAHDI, Aldein Alameh Hesam, PARVIZ MOHSEN, Ahmadi Basir Zahra. Evaluation of Ficus carica Linn Fruit Extracts on Formalin Induced Pain in the Male Rat Paw. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH[Internet]. 2019;17(3):0-0. Available from: https://sid.ir/paper/763736/en

IEEE: Copy

SAYID MAHDI MIRGHAZANFARI, Hesam Aldein Alameh, MOHSEN PARVIZ, and Zahra Ahmadi Basir, “Evaluation of Ficus carica Linn Fruit Extracts on Formalin Induced Pain in the Male Rat Paw,” ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, vol. 17, no. 3, pp. 0–0, 2019, [Online]. Available: https://sid.ir/paper/763736/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops