EFFECT OF INTRAHIPPOCAMPAL INJECTION OF VERAPAMIL DURING CHEMICAL KINDLING ON MORRIS WATER MAZE LEARNING IN RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

PALIZVAN M.R.; GHAZNAVI E.; AMINI KOMIJANI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES Year:2005 | Volume:10 | Issue:2 (Serial number 36) Page(s): 1-9

Download Full-Text

Persian Verion

View:

768

Download:

Cites:

Information Journal Paper

Title

EFFECT OF INTRAHIPPOCAMPAL INJECTION OF VERAPAMIL DURING CHEMICAL KINDLING ON MORRIS WATER MAZE LEARNING IN RATS

Author(s)

PALIZVAN M.R. | GHAZNAVI E. | AMINI KOMIJANI A. | Issue Writer Certificate

Keywords

PENTYLENETETRAZOLQ2

KINDLINGQ2

VERAPAMILQ3

HIPPOCAMPUSQ2

SPATIAL LEARNINGQ3

Abstract

Background and Aim: In this study the effect of voltage dependent calcium channels of the CA1 region of the HIPPOCAMPUS on the PENTYLENETETRAZOL (PTZ) induced KINDLING and resultant learning deficits were investigated in rats. Materials and Methods: In this study the rats were divided into three groups. In the control group artificial cerebrospinal fluid (ACSF) was infused bilaterally into the HIPPOCAMPUS. In the kindled group, 20 min after infusion of ACSF, KINDLING was established in rats by injection of subconvulsive dose (37.5 mg/kg i.p.) of PTZ intraperitoneally. The rats were kept under observation for 20 minutes and the convulsive responses were graded on the basis of a 5-scale criterion. In the test or VERAPAMILe group, VERAPAMILe, were injected in the HIPPOCAMPUS (4 mg/4 min) and after 20 min KINDLING was established in rats by use of PTZ. One month after induction of KINDLING SPATIAL LEARNING and memory were tested by Morris water maze in all three groups. Results: The results of this study were suggestive of a significant decrease of SPATIAL LEARNING in the rats of the test group. Conclusion: In this research, intera-hippcampal injection of VERAPAMIL significantly impaired SPATIAL LEARNING in rats.

Cites

No record.

References

No record.

Cite

APA: Copy

PALIZVAN, M.R., GHAZNAVI, E., & AMINI KOMIJANI, A.. (2005). EFFECT OF INTRAHIPPOCAMPAL INJECTION OF VERAPAMIL DURING CHEMICAL KINDLING ON MORRIS WATER MAZE LEARNING IN RATS. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, 10(2 (Serial number 36)), 1-9. SID. https://sid.ir/paper/76389/en

Vancouver: Copy

PALIZVAN M.R., GHAZNAVI E., AMINI KOMIJANI A.. EFFECT OF INTRAHIPPOCAMPAL INJECTION OF VERAPAMIL DURING CHEMICAL KINDLING ON MORRIS WATER MAZE LEARNING IN RATS. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2005;10(2 (Serial number 36)):1-9. Available from: https://sid.ir/paper/76389/en

IEEE: Copy

M.R. PALIZVAN, E. GHAZNAVI, and A. AMINI KOMIJANI, “EFFECT OF INTRAHIPPOCAMPAL INJECTION OF VERAPAMIL DURING CHEMICAL KINDLING ON MORRIS WATER MAZE LEARNING IN RATS,” SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, vol. 10, no. 2 (Serial number 36), pp. 1–9, 2005, [Online]. Available: https://sid.ir/paper/76389/en

Related Journal Papers