مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

184
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

127
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Molecular Authentication of Radix Behen Albi ( Bahman Sefid ) Commercial Products Reveals Widespread Adulteration

Pages

  57-64

Abstract

 Background and objectives: The roots of Centaurea behen L., (Asteraceae) known as Radix Behen Albi are used as an aphrodisiac, anti-lithiasis and general tonic. It is available as dried or powdered roots in the herbal markets of Iran. Confirming the identity of this medicinal root using conventional methods is challenging because of lack of the diagnostic characters and market samples are easy to misidentify or adulterate. Methods: This study aimed to authenticate 13 Radix Behen Albi samples purchased from different herbal markets in Iran and to identify the potential adulterants through DNA barcoding. Nuclear (nrITS) and plastid (trnL-F spacer, matK and rbcL) DNA regions were used as barcoding markers. A reference database was compiled using sequences from herbarium voucher specimens and publicly available sequences. Results: Among used barcode regions nrITS was the best marker for species identification followed by trnL-F spacer. MatK and rbcL were able to identify samples to the family level. This study showed that none of the market samples belonged to the authentic Centaurea behen L. Sixty-nine percent of samples were Cousinia spp. (Asteraceae), 23% Korshinskya spp. (Apiaceae) and 8% Crambe spp. (Brassicaceae). This substitution does not only hinder consumers obtain the desired medicinal effects of Radix Behen Albi but also raises concerns about the pharmacovigilance of this medicinal root sold in the markets. Conclusion: The present study shows the need for monitoring and authentication of crude herbal drugs in the markets of Iran, and that DNA barcoding is a suitable tool for this purpose.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    Ghorbani, Abdolbaset, MOSADDEGH, MAHMOUD, ESMAEILI, SOMAYEH, & Boer, Hugo De. (2020). Molecular Authentication of Radix Behen Albi ( Bahman Sefid ) Commercial Products Reveals Widespread Adulteration. RESEARCH JOURNAL OF PHARMACOGNOSY, 7(4), 57-64. SID. https://sid.ir/paper/764320/en

    Vancouver: Copy

    Ghorbani Abdolbaset, MOSADDEGH MAHMOUD, ESMAEILI SOMAYEH, Boer Hugo De. Molecular Authentication of Radix Behen Albi ( Bahman Sefid ) Commercial Products Reveals Widespread Adulteration. RESEARCH JOURNAL OF PHARMACOGNOSY[Internet]. 2020;7(4):57-64. Available from: https://sid.ir/paper/764320/en

    IEEE: Copy

    Abdolbaset Ghorbani, MAHMOUD MOSADDEGH, SOMAYEH ESMAEILI, and Hugo De Boer, “Molecular Authentication of Radix Behen Albi ( Bahman Sefid ) Commercial Products Reveals Widespread Adulteration,” RESEARCH JOURNAL OF PHARMACOGNOSY, vol. 7, no. 4, pp. 57–64, 2020, [Online]. Available: https://sid.ir/paper/764320/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button