مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

Short Communication: A Pilot Study of FDG-PET/CT in Polycythemia Vera Using Global Analysis Techniques

Pages

  64-68

Abstract

 Objective(s): Functional imaging presents a non-invasive process that may capture the hyper-metabolic nature of red bone marrow in myeloproliferative neoplasms, such as polycythemia vera (PV). Methods: This study analyzed the FDG-PET/CT scans (n=12) of six patients diagnosed with PV and six age-sex matched controls using a quantitative global analysis methodology. Results: All PV patients had elevated activities in the bone marrow of each skeletal structure as compared to matched controls with respect to mean standardized uptake value (femoral neck p=0. 01, lumbar spine p=0. 02, pelvis p=0. 002, sternum p=0. 04). Notable variations in splenic uptake were observed among the treated and untreated PV patients. Conclusion: Our study exemplifies the potential utility of PET in reflecting hyperactive bone marrow activity related to PV. Future studies may further substantiate and elaborate on the use of PET-derived metabolic data in PV.

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    Cite

    APA: Copy

    Ayubcha, Cyrus, Hosoya, Hitomi, Mehdizadeh Seraj, Siavash, Zirakchian Zadeh, Mahdi, Werner, Thomas, & Alavi, Abass. (2020). Short Communication: A Pilot Study of FDG-PET/CT in Polycythemia Vera Using Global Analysis Techniques. ASIA OCEANIA JOURNAL OF NUCLEAR MEDICINE AND BIOLOGY, 8(1), 64-68. SID. https://sid.ir/paper/765799/en

    Vancouver: Copy

    Ayubcha Cyrus, Hosoya Hitomi, Mehdizadeh Seraj Siavash, Zirakchian Zadeh Mahdi, Werner Thomas, Alavi Abass. Short Communication: A Pilot Study of FDG-PET/CT in Polycythemia Vera Using Global Analysis Techniques. ASIA OCEANIA JOURNAL OF NUCLEAR MEDICINE AND BIOLOGY[Internet]. 2020;8(1):64-68. Available from: https://sid.ir/paper/765799/en

    IEEE: Copy

    Cyrus Ayubcha, Hitomi Hosoya, Siavash Mehdizadeh Seraj, Mahdi Zirakchian Zadeh, Thomas Werner, and Abass Alavi, “Short Communication: A Pilot Study of FDG-PET/CT in Polycythemia Vera Using Global Analysis Techniques,” ASIA OCEANIA JOURNAL OF NUCLEAR MEDICINE AND BIOLOGY, vol. 8, no. 1, pp. 64–68, 2020, [Online]. Available: https://sid.ir/paper/765799/en

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