Effect of Hydroalcoholic Extract of Althaea officinalis Root on Improving Chemotherapy-Induced Stomatitis: A Randomized, Double-Blind, Clinical Trial

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Ghorbani Mohamad Sadegh; TAGHADOSI MOHSEN; AKBARI HOSSEIN; Sharifi Mehran

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Nursing and Midwifery Studies Year:2019 | Volume:8 | Issue:1 Page(s): 14-20

Download Full-Text

View:

140

Download:

118

Cites:

Information Journal Paper

Title

Effect of Hydroalcoholic Extract of Althaea officinalis Root on Improving Chemotherapy-Induced Stomatitis: A Randomized, Double-Blind, Clinical Trial

Author(s)

Ghorbani Mohamad Sadegh | TAGHADOSI MOHSEN | AKBARI HOSSEIN | Sharifi Mehran | Issue Writer Certificate

Keywords

Althaea

Cancer

Chemotherapy

Mucositis

Stomatitis

Abstract

Background: Stomatitis is a common and serious side effect of Chemotherapy. It is associated with multiple consequences such as pain, oral intake disorder, infection, bleeding, and failure of Cancer treatments. Objectives: This study aimed to compare the improving effect of mouthwash containing hydroalcoholic extract of Althaea root and routine mouthwash on Chemotherapy‑ induced Stomatitis. Methods: This double‑ blind, randomized, controlled clinical trial was conducted on Chemotherapy‑ induced Stomatitis cases (n = 50) in the Oncology Department of Shahid Beheshti Hospital, Kashan, Iran, in 2016. Patients were assigned into two groups through permuted‑ block randomization. The control group was treated with 15 mL of routine mouthwash solution 4 times a day for 14 days whereas the experimental group was treated with a mixture of routine solution and Althaea root extract (50/50). The severity of Stomatitis was assessed at baseline, 7th, and 14th days of intervention using the Worlds Health Organization’ s Stomatitis evaluation checklist. Data analysis was conducted using the Chi‑ square and Fisher’ s exact tests and repeated measure analysis of variance. Results: At baseline, the mean score of Stomatitis in the control group was 1. 92 ± 0. 70, which reduced to 0. 96 ± 0. 68 and 0. 92 ± 0. 64 on the 7th and 14th days after the intervention, respectively. In the experimental group, the mean score of Stomatitis was 1. 84 ± 0. 74 at baseline, which reduced to 1. 00 ± 0. 82 and 0. 44 ± 0. 76 on the 7th and 14th days after the intervention, respectively (P = 0. 015). Conclusion: Mouthwash solution containing Althaea officinalis root extract could improve Stomatitis caused by Chemotherapy more than the routine mouthwash solution. Thus, the mentioned herb has the potential to be used concurrently with Chemotherapy agents to alleviate the occurrence of Stomatitis.

Cites

No record.

References

No record.

Cite

APA: Copy

Ghorbani, Mohamad Sadegh, TAGHADOSI, MOHSEN, AKBARI, HOSSEIN, & Sharifi, Mehran. (2019). Effect of Hydroalcoholic Extract of Althaea officinalis Root on Improving Chemotherapy-Induced Stomatitis: A Randomized, Double-Blind, Clinical Trial. NURSING AND MIDWIFERY STUDIES, 8(1), 14-20. SID. https://sid.ir/paper/765994/en

Vancouver: Copy

Ghorbani Mohamad Sadegh, TAGHADOSI MOHSEN, AKBARI HOSSEIN, Sharifi Mehran. Effect of Hydroalcoholic Extract of Althaea officinalis Root on Improving Chemotherapy-Induced Stomatitis: A Randomized, Double-Blind, Clinical Trial. NURSING AND MIDWIFERY STUDIES[Internet]. 2019;8(1):14-20. Available from: https://sid.ir/paper/765994/en

IEEE: Copy

Mohamad Sadegh Ghorbani, MOHSEN TAGHADOSI, HOSSEIN AKBARI, and Mehran Sharifi, “Effect of Hydroalcoholic Extract of Althaea officinalis Root on Improving Chemotherapy-Induced Stomatitis: A Randomized, Double-Blind, Clinical Trial,” NURSING AND MIDWIFERY STUDIES, vol. 8, no. 1, pp. 14–20, 2019, [Online]. Available: https://sid.ir/paper/765994/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops