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Information Journal Paper

Title

The Effect of Neutron Contamination on Probability of Secondary Cancer in Radiotherapy of Pelvic Region with 18-MV Photons

Pages

  222-`227

Abstract

 Background: Todays, Radiotherapy with high-energy photons is used as a common modality for Cancer treatment. Unfortunately, high-energy photons can produce unwanted Neutrons, and subsequently lead to increase the risk of Secondary Cancer in unshielded healthy organs. Methods: Using Monte Carlo (MC) code (MCNPX® ), the main parts of a typical Medical Linear Accelerator (LINAC) was modeled in 18 MV. Then, neutron source strength (Q) of the LINAC and neutron mean energy were evaluated for different treatment fields, and also different points at the treatment table. Additionally, to estimate the Probability of Secondary Cancer risk, the neutron equivalent dose was calculated at some of the human’ s critical organs. For this purpose, the female medical internal radiation dosimetry (MIRD) phantom was included in the MC simulations. Findings: The Q was found as 1. 25-1. 38 (all in 1012 n/Gy) for different treatment fields meaning significant portion of Neutrons with a mean energy of 0. 59-0. 90 MeV around the LINAC. Additionally, the total Secondary Cancer risk in unshielded healthy organs was calculated as 0. 0924% which maximum and minimum were related to stomach (0. 0216%) and thyroid (0. 0005%), respectively. Conclusion: Regarding the estimated values for the Probability of Secondary Cancer risk, it is suggested that in conventional Radiotherapy of deeply seated tumors, the 15-MV photons are preferred instead of using 18-MV photons due to their less biological side effects.

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    APA: Copy

    KARIMI, AMIR HOSSEIN, CHEGENI, NAHID, JABBARI, IRAJ, & Hassanvand, Maryam. (2019). The Effect of Neutron Contamination on Probability of Secondary Cancer in Radiotherapy of Pelvic Region with 18-MV Photons. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 37(519 ), 222-`227. SID. https://sid.ir/paper/767767/en

    Vancouver: Copy

    KARIMI AMIR HOSSEIN, CHEGENI NAHID, JABBARI IRAJ, Hassanvand Maryam. The Effect of Neutron Contamination on Probability of Secondary Cancer in Radiotherapy of Pelvic Region with 18-MV Photons. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2019;37(519 ):222-`227. Available from: https://sid.ir/paper/767767/en

    IEEE: Copy

    AMIR HOSSEIN KARIMI, NAHID CHEGENI, IRAJ JABBARI, and Maryam Hassanvand, “The Effect of Neutron Contamination on Probability of Secondary Cancer in Radiotherapy of Pelvic Region with 18-MV Photons,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 37, no. 519 , pp. 222–`227, 2019, [Online]. Available: https://sid.ir/paper/767767/en

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    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
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