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Information Journal Paper

Title

The Relationship between Graft Function and Liver Function after Kidney Transplantation: A Retrospective Cohort Study

Pages

  84-90

Abstract

 Introduction After kidney transplantation, several factors should be checked to predict the risk of rejection. Liver enzymes are such predicting factors so liver function test abnormalities (LFTA) can consider the rejection possibility in kidney transplant recipients (KTR). Methods Through a retrospective cohort study, 659 KTR were studied. The source of all grafts was from deceased donors. Amongst these cases, 67 patients showed a significant rise in creatinine as the rejection indication. Several liver indexes like alanine transaminase (ALT), aspartate transaminase (AST), direct bilirubin (Bil D), total bilirubin (Bil T), and liver ultrasound reports, gamma-glutamyl transpeptidase (GGT), alkaline phosphatase (ALP), prothrombin time (PT) INR in addition to creatinine were examined for three-six post-transplant in KTR. Results Our study exposed that liver functional tests regularly had considerable statistical differences between KTR with creatinine increase and with no creatinine increase. Despite these differences between the two groups AST, ALT and ALP serum levels were still within the normal range in both groups. The same result was seen over the Bil D, and Bil T. Conclusions Liver function test abnormalities can not adequately predict the rejection. Some other elements should be taken into consideration like inflammation factors like erythrocyte sedimentation rate (ESR or sed rate), and C-reactive protein (CRP).

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    APA: Copy

    AGHAMIR, SEYED MOHAMMAD KAZEM, JAMALI, RAIKA, Tamehri Zadeh, Seyed Saeed, KHAJAVI, ALIREZA, KHATAMI, FATEMEH, POURMAND, GHOLAMREZA, & DEHGHANI, SANAZ. (2019). The Relationship between Graft Function and Liver Function after Kidney Transplantation: A Retrospective Cohort Study. TRANSLATIONAL RESEARCH IN UROLOGY, 1(2), 84-90. SID. https://sid.ir/paper/767902/en

    Vancouver: Copy

    AGHAMIR SEYED MOHAMMAD KAZEM, JAMALI RAIKA, Tamehri Zadeh Seyed Saeed, KHAJAVI ALIREZA, KHATAMI FATEMEH, POURMAND GHOLAMREZA, DEHGHANI SANAZ. The Relationship between Graft Function and Liver Function after Kidney Transplantation: A Retrospective Cohort Study. TRANSLATIONAL RESEARCH IN UROLOGY[Internet]. 2019;1(2):84-90. Available from: https://sid.ir/paper/767902/en

    IEEE: Copy

    SEYED MOHAMMAD KAZEM AGHAMIR, RAIKA JAMALI, Seyed Saeed Tamehri Zadeh, ALIREZA KHAJAVI, FATEMEH KHATAMI, GHOLAMREZA POURMAND, and SANAZ DEHGHANI, “The Relationship between Graft Function and Liver Function after Kidney Transplantation: A Retrospective Cohort Study,” TRANSLATIONAL RESEARCH IN UROLOGY, vol. 1, no. 2, pp. 84–90, 2019, [Online]. Available: https://sid.ir/paper/767902/en

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