Apatinib for Treatment of Locally Advanced Rectal Angiosarcoma: A Case Report

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Chen Engeng; Xu Zhiyao; Cao Gaoyang; CHEN LIN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: Iranian Red Crescent Medical Journal Year:2020 | Volume:22 | Issue:7 Page(s): 0-0

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Title

Apatinib for Treatment of Locally Advanced Rectal Angiosarcoma: A Case Report

Author(s)

Chen Engeng | Xu Zhiyao | Cao Gaoyang | CHEN LIN | Issue Writer Certificate

Keywords

Case Report

Apatinib

Rectal Angiosarcoma

Abstract

Introduction: Primary coloRectal Angiosarcoma is a highly rare malignant tumor. There is no standard treatment method for this disease. No treatment of Rectal Angiosarcoma with Apatinib has been reported so far. Case Presentation: In the current study, an 87-year-old male presented with the symptoms of frequent defecation for more than one month in Hangzhou, China, in 2018. The patient was initially diagnosed with a rectal stromal tumor. The patient underwent ultrasound-guided transrectal mass puncture in the next treatment. However, immunohistochemical examinations confirmed the initial diagnosis of Rectal Angiosarcoma. The patient had advanced age and Rectal Angiosarcoma with metastasis; he had no surgical indications, and we tried to use Apatinib 250 mg/d treatment to control the progression of the lesion. Then, he received Apatinib, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2). The patient has been stable to Apatinib with a dose of 250 mg daily by now. Conclusions: Apatinib may play an important role in the treatment of unresectable angiosarcoma.

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APA: Copy

Chen, Engeng, Xu, Zhiyao, Cao, Gaoyang, & CHEN, LIN. (2020). Apatinib for Treatment of Locally Advanced Rectal Angiosarcoma: A Case Report. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 22(7), 0-0. SID. https://sid.ir/paper/768384/en

Vancouver: Copy

Chen Engeng, Xu Zhiyao, Cao Gaoyang, CHEN LIN. Apatinib for Treatment of Locally Advanced Rectal Angiosarcoma: A Case Report. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2020;22(7):0-0. Available from: https://sid.ir/paper/768384/en

IEEE: Copy

Engeng Chen, Zhiyao Xu, Gaoyang Cao, and LIN CHEN, “Apatinib for Treatment of Locally Advanced Rectal Angiosarcoma: A Case Report,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 22, no. 7, pp. 0–0, 2020, [Online]. Available: https://sid.ir/paper/768384/en

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