Assessing VEGF mRNA and miR-494 expression in peripheral blood collected from patients suffering from oral squamous cell carcinoma

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Masoum Khani Maryam; MOHAMADNIA ABDOLREZA; HOSSEINI FARZANEH; Bayat Parisa; BAHRAMI NAGHMEH

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Journal: JOURNAL OF CRANIOMAXILLOFACIAL RESEARCH Year:2019 | Volume:6 | Issue:1 Page(s): 34-38

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Title

Assessing VEGF mRNA and miR-494 expression in peripheral blood collected from patients suffering from oral squamous cell carcinoma

Author(s)

Keywords

Oral squamous cell carcinoma

Early diagnosis

VEGF mRNA

miR-494

Abstract

Introduction: Oral squamous cell carcinoma accounts for 2% of all cancers and also is one of the top 10 causes of death in humans. The goal of this article is to assess changes of VEGF mRNA and miR-494 expression. Materials and Methods: We chose 30 patients with OSCC and 30 healthy people (as a controlled group) and assess the rate of VEGF mRNA and miR-494 expression in peripheral blood with real-time PCR technique. Findings: VEGF mRNA marker was positive in 24 out of 30 patients. Also, miR-494 was positive in 20 out of 30 patients. Results: Overall based on this article’ s findings, results could count as a diagnostic screening test for OSCC detection in early steps of cancer.

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APA: Copy

Masoum Khani, Maryam, MOHAMADNIA, ABDOLREZA, HOSSEINI, FARZANEH, Bayat, Parisa, & BAHRAMI, NAGHMEH. (2019). Assessing VEGF mRNA and miR-494 expression in peripheral blood collected from patients suffering from oral squamous cell carcinoma. JOURNAL OF CRANIOMAXILLOFACIAL RESEARCH, 6(1), 34-38. SID. https://sid.ir/paper/769603/en

Vancouver: Copy

Masoum Khani Maryam, MOHAMADNIA ABDOLREZA, HOSSEINI FARZANEH, Bayat Parisa, BAHRAMI NAGHMEH. Assessing VEGF mRNA and miR-494 expression in peripheral blood collected from patients suffering from oral squamous cell carcinoma. JOURNAL OF CRANIOMAXILLOFACIAL RESEARCH[Internet]. 2019;6(1):34-38. Available from: https://sid.ir/paper/769603/en

IEEE: Copy

Maryam Masoum Khani, ABDOLREZA MOHAMADNIA, FARZANEH HOSSEINI, Parisa Bayat, and NAGHMEH BAHRAMI, “Assessing VEGF mRNA and miR-494 expression in peripheral blood collected from patients suffering from oral squamous cell carcinoma,” JOURNAL OF CRANIOMAXILLOFACIAL RESEARCH, vol. 6, no. 1, pp. 34–38, 2019, [Online]. Available: https://sid.ir/paper/769603/en

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