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Information Journal Paper

Title

Seroprevalence of Cytomegalovirus Antibodies by Electrochemiluminescence Method in Young Women Referred to the Clinical Laboratory, Sanandaj, Iran

Pages

  92-98

Abstract

 Background and aims: Maternal primary and recurrent infection of Cytomegalovirus (CMV) may be transmitted to the fetus during pregnancy and may have complications such as death or growth, along with the development retardation of the fetus and infant. The aim of this study was to determine the prevalence of immunoglobulin G (IgG) and immunoglobulin M (IgM) Antibodies against CMV in young Women, Sanandaj, Iran. Methods: To this end, 90 Women (15-40 years old) referring to a clinical laboratory were randomly selected and announced their informed consent to participate in this cross-sectional study. Demographic information and Women’ s data were collected, including pregnancy, history of abortion, and history of blood transfusion. Then, Women’ s sera were measured for CMV IgG and IgM Antibodies using the Electrochemiluminescence technique. Finally, the data were analyzed by SPSS statistical software. Results: The prevalence of IgG and IgM Antibodies against CMV in Women was 92. 2% (95% CI = 86. 5-97. 8) and 0%, respectively. In addition, the average CMV IgG antibody level was about 137. 52 ± 85. 215 SD IU/mL. The results revealed a significant statistical association between IgG antibody and pregnancy (P value = 0. 012) while there was no association between CMV IgG antibody and other demographic data. Conclusions: In general, high percentages of Women had CMV IgG antibody whereas 7. 8% of them were susceptible. They are expected to acquire CMV primary infection, and therefore, the screening of Antibodies to CMV is suggested for prenatal care.

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    Cite

    APA: Copy

    KHODABANDEHLOO, MAZAHER, & Sharifi, Pezhman. (2020). Seroprevalence of Cytomegalovirus Antibodies by Electrochemiluminescence Method in Young Women Referred to the Clinical Laboratory, Sanandaj, Iran. EPIDEMIOLOGY AND HEALTH SYSTEM JOURNAL (INTERNATIONAL JOURNAL OF EPIDEMIOLOGIC RESEARCH), 7(2), 92-98. SID. https://sid.ir/paper/774136/en

    Vancouver: Copy

    KHODABANDEHLOO MAZAHER, Sharifi Pezhman. Seroprevalence of Cytomegalovirus Antibodies by Electrochemiluminescence Method in Young Women Referred to the Clinical Laboratory, Sanandaj, Iran. EPIDEMIOLOGY AND HEALTH SYSTEM JOURNAL (INTERNATIONAL JOURNAL OF EPIDEMIOLOGIC RESEARCH)[Internet]. 2020;7(2):92-98. Available from: https://sid.ir/paper/774136/en

    IEEE: Copy

    MAZAHER KHODABANDEHLOO, and Pezhman Sharifi, “Seroprevalence of Cytomegalovirus Antibodies by Electrochemiluminescence Method in Young Women Referred to the Clinical Laboratory, Sanandaj, Iran,” EPIDEMIOLOGY AND HEALTH SYSTEM JOURNAL (INTERNATIONAL JOURNAL OF EPIDEMIOLOGIC RESEARCH), vol. 7, no. 2, pp. 92–98, 2020, [Online]. Available: https://sid.ir/paper/774136/en

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