PREVALENCE OF GLUCOSE -6- PHOSPHATE DEHYDROGENASE DEFICIENCY IN A STUDENT POPULATION IN YASUJ

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MIRZAEI ALI; FALAHZADEH ABARGHOUEI A.; HAGHBIN S.

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Journal: Armaghane Danesh Year:2000 | Volume:5 | Issue:17-18 Page(s): 63-67

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Information Journal Paper

Title

PREVALENCE OF GLUCOSE -6- PHOSPHATE DEHYDROGENASE DEFICIENCY IN A STUDENT POPULATION IN YASUJ

Author(s)

MIRZAEI ALI | FALAHZADEH ABARGHOUEI A. | HAGHBIN S. | Issue Writer Certificate

Keywords

FAVISMQ4

G6PDQ3

HEMOLYSISQ3

FAVA BEANSQ4

Abstract

Glucose- 6- phosphate dehydrogenase deficiency (G6PD) is the most common human enzymopathy. G6PD deficiency is an X-linked inherited disease and approximately 200 million people are affected worldwide. The G6PD variants with reduced activity (Mediterranean) produce FAVISM or may cause HEMOLYSIS after ingestion of FAVA BEANS (Vica Fava). The incidence of G6PD deficiency is most common in south and north of Iran. A cross - sectional study was done among school boy students. A multi- stage cluster sample of 300 students between 9-11 years old were randomly selected for determination of G6PD activity.1 milliliter of wholeblood anticoagulated with EDTA was collected and transferred to clinical laboratory immediately .We used t1uorescent spot test as screening test and we also analyzed clinical manifestations. 38 cases had G6PD deficiency (prevalence of 12.7%). The clinical manifestations were: no clinical manifestations were found (54%), 44%had presented with neonatal jaundice and 2% had suffered a FAVISM crisis. The prevalence of G6PD deficiency in Yasuj municipality was very high. Most of the carriers were asymptomatic; the most important clinical manifestations were neonatal jaundice and FAVISM. The screening test used is efficient for unmistakable hemizygote detection.

Cites

بررسی کمبود آنزیم G6PD به وسیله آزمایش احیای NADP در نوزادان مبتلا به زردی

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APA: Copy

MIRZAEI, ALI, FALAHZADEH ABARGHOUEI, A., & HAGHBIN, S.. (2000). PREVALENCE OF GLUCOSE -6- PHOSPHATE DEHYDROGENASE DEFICIENCY IN A STUDENT POPULATION IN YASUJ. ARMAGHAN DANESH, 5(17-18), 63-67. SID. https://sid.ir/paper/77513/en

Vancouver: Copy

MIRZAEI ALI, FALAHZADEH ABARGHOUEI A., HAGHBIN S.. PREVALENCE OF GLUCOSE -6- PHOSPHATE DEHYDROGENASE DEFICIENCY IN A STUDENT POPULATION IN YASUJ. ARMAGHAN DANESH[Internet]. 2000;5(17-18):63-67. Available from: https://sid.ir/paper/77513/en

IEEE: Copy

ALI MIRZAEI, A. FALAHZADEH ABARGHOUEI, and S. HAGHBIN, “PREVALENCE OF GLUCOSE -6- PHOSPHATE DEHYDROGENASE DEFICIENCY IN A STUDENT POPULATION IN YASUJ,” ARMAGHAN DANESH, vol. 5, no. 17-18, pp. 63–67, 2000, [Online]. Available: https://sid.ir/paper/77513/en

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