POLYMORPHISM IN CCR4 GENE (1014 C/T) IN PATIENTS WITH BREAST CARCINOMA FROM THE SOUTH OF IRAN

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MOGHADDASI F.; HAGHSHENAS M.R.; NAEIMI S.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Armaghane Danesh Year:2013 | Volume:18 | Issue:1 (73) Page(s): 76-85

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Title

POLYMORPHISM IN CCR4 GENE (1014 C/T) IN PATIENTS WITH BREAST CARCINOMA FROM THE SOUTH OF IRAN

Author(s)

MOGHADDASI F. | HAGHSHENAS M.R. | NAEIMI S. | Issue Writer Certificate

Keywords

POLYMORPHISMQ2

CCR4Q2

BREAST CANCERQ2

Abstract

Background & aim: CCR4 gene POLYMORPHISM at position C/T1014 has been associated with changes in mRNA stability and is involved expression of this molecule. The aim of this study was to investigate CCR4 gene POLYMORPHISM at position 1014 C/T in breast carcinoma patients in southern Iran.Methods: In this case-control study, 150 women with breast carcinoma and 160 healthy women as controls were included. PCR-RFLP method was used to genotyping of CCR4, receptor gene. The data were analyzed using chi-square and Fisher.Results: Genotype frequencies of CC, CT and TT, in case group were 57.8, 35.1 & 7.1%, where as in control group showed 54.4, 39.4 & 6.2% respectively. In addition, C and T allele of the cases were, 75.3 & 24.7% and in control group 74.1 & 25.9% respectively (p>0.05).Conclusion: CCR4 gene POLYMORPHISM has no role in increasing of susceptibility to BREAST CANCER in the south of Iran population.

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APA: Copy

MOGHADDASI, F., HAGHSHENAS, M.R., & NAEIMI, S.. (2013). POLYMORPHISM IN CCR4 GENE (1014 C/T) IN PATIENTS WITH BREAST CARCINOMA FROM THE SOUTH OF IRAN. ARMAGHAN DANESH, 18(1 (73)), 76-85. SID. https://sid.ir/paper/77560/en

Vancouver: Copy

MOGHADDASI F., HAGHSHENAS M.R., NAEIMI S.. POLYMORPHISM IN CCR4 GENE (1014 C/T) IN PATIENTS WITH BREAST CARCINOMA FROM THE SOUTH OF IRAN. ARMAGHAN DANESH[Internet]. 2013;18(1 (73)):76-85. Available from: https://sid.ir/paper/77560/en

IEEE: Copy

F. MOGHADDASI, M.R. HAGHSHENAS, and S. NAEIMI, “POLYMORPHISM IN CCR4 GENE (1014 C/T) IN PATIENTS WITH BREAST CARCINOMA FROM THE SOUTH OF IRAN,” ARMAGHAN DANESH, vol. 18, no. 1 (73), pp. 76–85, 2013, [Online]. Available: https://sid.ir/paper/77560/en

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