مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

The first rare and fatal case of invasive aspergillosis of spinal cord due to Aspergillus nidulans in an Iranian child with chronic granulomatosis disease: review of literature

Pages

  55-60

Abstract

 Background and Purpose: Invasive aspergillosis (IA) of the central nervous system (CNS) is a devastating complication which is rarely reported in immunocompromised children. In this case presentation, we reported a rare and fatal IA with Spinal cord involvement in a 10-year-old child with X-linked Chronic granulomatosis disease (CGD). Case report: The child had a previous history of pulmonary tuberculosis. A cervical spine X-ray revealed the involvement of cervical vertebrae (T4/T5) and ribs causing Spinal cord compression and epidural abscess. The patient underwent a decompressive laminectomy and mass removal. The histopathology and culture results suggested IA. Despite the aggressive and prolonged therapy, he died within one year. Aspergillus nidulans was identified as the causative agent based on morphological and molecular studies. Conclusion: This synopsis represents the aggressive behavior of infection caused by A. nidulans in the CGD patient.

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  • Cite

    APA: Copy

    Tavakoli, Mahin, HEDAYATI, MOHAMMAD TAGHI, MIRHENDI, HOSSEIN, NOURIPOUR SISAKHT, SADEGH, Hedayati, Newsha, SAGHAFI, FATEMEH, & MAMISHI, SETAREH. (2020). The first rare and fatal case of invasive aspergillosis of spinal cord due to Aspergillus nidulans in an Iranian child with chronic granulomatosis disease: review of literature. CURRENT MEDICAL MYCOLOGY, 6(1), 55-60. SID. https://sid.ir/paper/776616/en

    Vancouver: Copy

    Tavakoli Mahin, HEDAYATI MOHAMMAD TAGHI, MIRHENDI HOSSEIN, NOURIPOUR SISAKHT SADEGH, Hedayati Newsha, SAGHAFI FATEMEH, MAMISHI SETAREH. The first rare and fatal case of invasive aspergillosis of spinal cord due to Aspergillus nidulans in an Iranian child with chronic granulomatosis disease: review of literature. CURRENT MEDICAL MYCOLOGY[Internet]. 2020;6(1):55-60. Available from: https://sid.ir/paper/776616/en

    IEEE: Copy

    Mahin Tavakoli, MOHAMMAD TAGHI HEDAYATI, HOSSEIN MIRHENDI, SADEGH NOURIPOUR SISAKHT, Newsha Hedayati, FATEMEH SAGHAFI, and SETAREH MAMISHI, “The first rare and fatal case of invasive aspergillosis of spinal cord due to Aspergillus nidulans in an Iranian child with chronic granulomatosis disease: review of literature,” CURRENT MEDICAL MYCOLOGY, vol. 6, no. 1, pp. 55–60, 2020, [Online]. Available: https://sid.ir/paper/776616/en

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