A Review on Ocular Novel Drug Delivery Systems of Antifungal Drugs: Functional Evaluation and Comparison of Conventional and Novel Dosage Forms

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Mehrandish Saba; MIRZAEEI SHAHLA

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Journal Paper

Paper Information

Journal: Advanced Pharmaceutical Bulletin Year:2021 | Volume:11 | Issue:1 Page(s): 28-38

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Title

A Review on Ocular Novel Drug Delivery Systems of Antifungal Drugs: Functional Evaluation and Comparison of Conventional and Novel Dosage Forms

Author(s)

Mehrandish Saba | MIRZAEEI SHAHLA | Issue Writer Certificate

Keywords

Antifungal drugs

Conventional dosage forms

Novel drug delivery systems

Ocular drug delivery

Abstract

Ocular fungal infections affect more than one million people annually worldwide. They can lead to impaired vision or even complete blindness, so they should be treated immediately to prevent such consequences. Although topical administration has always been the most common route of Ocular drug delivery owing to high patient acceptance, reduced side effects, and the possibility of self-administration, its limited ocular bioavailability poses a major challenge. As a result, attention has recently been drawn to the design and development of Novel drug delivery systems (NDDS) that can overcome the challenges of Conventional dosage forms. This research is the first to review and classify the studies which have designed and developed topical ocular NDDS with the aim to compare the performance and antifungal activity of these novel systems with conventional forms. According to the results, all studies seemed to confirm the superiority of NDDS over conventional forms in cases of released and permeated drug and antifungal activity. The NDDS were used specifically to improve ocular delivery by slowing down the release rate, increasing drug permeation, and subsequently increasing the antifungal effects of the active pharmaceutical ingredients. Hence, further studies on NDDS may aid the optimization of Ocular drug delivery of Antifungal drugs.

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APA: Copy

Mehrandish, Saba, & MIRZAEEI, SHAHLA. (2021). A Review on Ocular Novel Drug Delivery Systems of Antifungal Drugs: Functional Evaluation and Comparison of Conventional and Novel Dosage Forms. ADVANCED PHARMACEUTICAL BULLETIN, 11(1), 28-38. SID. https://sid.ir/paper/777436/en

Vancouver: Copy

Mehrandish Saba, MIRZAEEI SHAHLA. A Review on Ocular Novel Drug Delivery Systems of Antifungal Drugs: Functional Evaluation and Comparison of Conventional and Novel Dosage Forms. ADVANCED PHARMACEUTICAL BULLETIN[Internet]. 2021;11(1):28-38. Available from: https://sid.ir/paper/777436/en

IEEE: Copy

Saba Mehrandish, and SHAHLA MIRZAEEI, “A Review on Ocular Novel Drug Delivery Systems of Antifungal Drugs: Functional Evaluation and Comparison of Conventional and Novel Dosage Forms,” ADVANCED PHARMACEUTICAL BULLETIN, vol. 11, no. 1, pp. 28–38, 2021, [Online]. Available: https://sid.ir/paper/777436/en

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