مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

A New Treatment Method in Hepatocellular Carcinoma by MicroRNAs

Pages

  451-456

Abstract

 Objectives: Hepatocellular carcinoma (HCC) is considered as the most incidence form of cancer in the human liver and the main reason for worldwide cancer death. In addition, HCC is a common form of cancer in Africa and Asia and a global health issue. Thus, efforts should be made to improve treatment strategies and prognosis in HCC for recognizing novel prognostic and predictive markers. Methods: The present study reviewed recently published studies that were identified from the National Institutes of Health’ s PubMed database, Latin American Literature in Health Sciences, and Scientific Electronic Library Online. To this end, several key terms were searched, including “ Hepatocellular carcinoma” AND “ diagnosis” AND “ hepatic resection” , miRNA, and Mesh (Medical Subject Headings) consisting of miRNA “ Hepatocellular carcinoma” . Results: Both physiological and pathological processes such as development can be altered by the function and expression modifying of miRNA. The findings revealed that miR-101, miR-106, miR-130a, miR-515-5p, miR-199a, and miR-34a-5p have a considerable connection with tumor size in HCC patients. Conclusions: In general, several reports indicated that more than half of the miRNAs genes are located in cancer-associated genomic regions or fragile sites. Considering the reports regarding the important roles of miRNAs in cancer, their potential as prognostic or diagnostics markers is confirmed by a long list of studies and miRNA markers that could be used for cancer diagnosis are becoming available

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    Cite

    APA: Copy

    Asefy, Zahra, Shokuhi, Behrooz, ABHARI, ALIREZA, LATIFI, ZEINAB, Soltan Ahmad, Saeed Nazari, SAMADI, NASER, Hoseinnejhad, Sirus, Tanomand, Asgar, & NOURI, MOHAMMAD. (2020). A New Treatment Method in Hepatocellular Carcinoma by MicroRNAs. CRESCENT JOURNAL OF MEDICAL AND BIOLOGICAL SCIENCES, 7(4), 451-456. SID. https://sid.ir/paper/777446/en

    Vancouver: Copy

    Asefy Zahra, Shokuhi Behrooz, ABHARI ALIREZA, LATIFI ZEINAB, Soltan Ahmad Saeed Nazari, SAMADI NASER, Hoseinnejhad Sirus, Tanomand Asgar, NOURI MOHAMMAD. A New Treatment Method in Hepatocellular Carcinoma by MicroRNAs. CRESCENT JOURNAL OF MEDICAL AND BIOLOGICAL SCIENCES[Internet]. 2020;7(4):451-456. Available from: https://sid.ir/paper/777446/en

    IEEE: Copy

    Zahra Asefy, Behrooz Shokuhi, ALIREZA ABHARI, ZEINAB LATIFI, Saeed Nazari Soltan Ahmad, NASER SAMADI, Sirus Hoseinnejhad, Asgar Tanomand, and MOHAMMAD NOURI, “A New Treatment Method in Hepatocellular Carcinoma by MicroRNAs,” CRESCENT JOURNAL OF MEDICAL AND BIOLOGICAL SCIENCES, vol. 7, no. 4, pp. 451–456, 2020, [Online]. Available: https://sid.ir/paper/777446/en

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