DOSIMETRIC CALCULATIONS OF A RADIOACTIVE EYE PLAQUE USED IN MANAGEMENT OF OCULAR MELANOMA USING MONTE CARLO SIMULATIONS

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SHOKRANI P.; RAEIS ALI GH.R.; JANATI ESFAHANI A.

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Journal: Armaghane Danesh Year:2009 | Volume:14 | Issue:3 (55) Page(s): 113-120

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Title

DOSIMETRIC CALCULATIONS OF A RADIOACTIVE EYE PLAQUE USED IN MANAGEMENT OF OCULAR MELANOMA USING MONTE CARLO SIMULATIONS

Author(s)

SHOKRANI P. | RAEIS ALI GH.R. | JANATI ESFAHANI A. | Issue Writer Certificate

Keywords

BRACHYTHERAPYQ2

DOSIMETRIC CALCULATIONQ3

MONTE CARLOQ3

Abstract

Introduction & Objective: BRACHYTHERAPY using I-125 radioactive seeds in removable episcleral plaques (EP) is often used in treatment of ocular malignant melanoma. Some radioactive seeds are fixed in a gold bowl-shaped plaque. The plaque is sutured to the sclera surface corresponding to the base of the intraocular tumor, allowing for a localized radiation dose delivery to the tumor.Minimum target doses as high as 85Gy are directed at malignant tumor. The aim of this study was to develop a MONTE CARLO simulation of an ocular plaque in order to calculate the resulting isodose distributions.Materials & Methods: The MCNP-4C MONTE CARLO code is used to simulate the plan of an episcleral plaque treatment. A 20-mm Collaborative Ocular Melanoma Study (COMS) plaque with 3, I-125 seed of model 6711 was used. Resulting dose distributions, including central axis dose and off-axis dose profiles, were calculated in a water phantom with 12mm radius. The calculated dose distributions were compared to the corresponding dose measured by Knuten et al., 2001.Results: Central axis dose calculations represent a rapid dose fall off, which is an important factor in selection of appropriate eye plaque for management of tumors with known dimension.Calculated off-axis dose profiles show decreased dose uniformity at distances close to the plaque. Increasing of distance from the plaque resulted in increasing of the dose uniformity.Conclusion: MONTE CARLO simulation of eye plaques can be used as a useful tool in process of design, development and treatment planning of ocular radioactive plaques.

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APA: Copy

SHOKRANI, P., RAEIS ALI, GH.R., & JANATI ESFAHANI, A.. (2009). DOSIMETRIC CALCULATIONS OF A RADIOACTIVE EYE PLAQUE USED IN MANAGEMENT OF OCULAR MELANOMA USING MONTE CARLO SIMULATIONS. ARMAGHAN DANESH, 14(3 (55)), 113-120. SID. https://sid.ir/paper/78020/en

Vancouver: Copy

SHOKRANI P., RAEIS ALI GH.R., JANATI ESFAHANI A.. DOSIMETRIC CALCULATIONS OF A RADIOACTIVE EYE PLAQUE USED IN MANAGEMENT OF OCULAR MELANOMA USING MONTE CARLO SIMULATIONS. ARMAGHAN DANESH[Internet]. 2009;14(3 (55)):113-120. Available from: https://sid.ir/paper/78020/en

IEEE: Copy

P. SHOKRANI, GH.R. RAEIS ALI, and A. JANATI ESFAHANI, “DOSIMETRIC CALCULATIONS OF A RADIOACTIVE EYE PLAQUE USED IN MANAGEMENT OF OCULAR MELANOMA USING MONTE CARLO SIMULATIONS,” ARMAGHAN DANESH, vol. 14, no. 3 (55), pp. 113–120, 2009, [Online]. Available: https://sid.ir/paper/78020/en

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