Formulation and Applications of Lipid-Based Nanovehicles: Spotlight on Self-emulsifying Systems (Mini Review)

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Mehanna Mohammed M.; Mneimneh Amina Tarek

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Journal Paper

Paper Information

Journal: Advanced Pharmaceutical Bulletin Year:2021 | Volume:11 | Issue:1 Page(s): 56-67

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Information Journal Paper

Title

Formulation and Applications of Lipid-Based Nanovehicles: Spotlight on Self-emulsifying Systems (Mini Review)

Author(s)

Mehanna Mohammed M. | Mneimneh Amina Tarek | Issue Writer Certificate

Keywords

Drug delivery

Lipids

Nanocarriers

Nanoemulsion

Solubility

Self-nanoemulsifying system

Abstract

The Drug delivery investigation field is continuously widened and adapted to overcome many factors such as poor drug Solubility, absorption, rapid metabolism, the variability of drug plasma levels, cellular efflux and many others. Due to resemblance to body constituents and their biocompatibility, Lipids offer a promising scheme for poorly water-soluble and lipophilic drugs. Various nanoparticles including vesicular systems, lipid particulate systems, and emulsion systems provide some unique benefits as pharmaceutical carriers in drug and biomolecules delivery systems. Nowadays synthesis is directed toward simple, costless techniques, therefore, self-emulsifying systems have gained superiority over the other carriers. Self nano-emulsifying systems composed of oil, surfactant, and co-surfactant emulsified upon contact with an aqueous medium, has been widely exploited. This review attempts to provide a comprehensive interpretation of different types of lipid-based carriers emphasizing on the Self-nanoemulsifying system, why it is gaining interest, formulation, composition, and applications.

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APA: Copy

Mehanna, Mohammed M., & Mneimneh, Amina Tarek. (2021). Formulation and Applications of Lipid-Based Nanovehicles: Spotlight on Self-emulsifying Systems (Mini Review). ADVANCED PHARMACEUTICAL BULLETIN, 11(1), 56-67. SID. https://sid.ir/paper/780373/en

Vancouver: Copy

Mehanna Mohammed M., Mneimneh Amina Tarek. Formulation and Applications of Lipid-Based Nanovehicles: Spotlight on Self-emulsifying Systems (Mini Review). ADVANCED PHARMACEUTICAL BULLETIN[Internet]. 2021;11(1):56-67. Available from: https://sid.ir/paper/780373/en

IEEE: Copy

Mohammed M. Mehanna, and Amina Tarek Mneimneh, “Formulation and Applications of Lipid-Based Nanovehicles: Spotlight on Self-emulsifying Systems (Mini Review),” ADVANCED PHARMACEUTICAL BULLETIN, vol. 11, no. 1, pp. 56–67, 2021, [Online]. Available: https://sid.ir/paper/780373/en

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