Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

92
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

36
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Tau Abnormalities and Autophagic Defects in Neurodegenerative Disorders; A Feed-forward Cycle (review article)

Pages

  0-0

Abstract

 Abnormal deposition of misfolded proteins is a neuropathological characteristic shared by many neurodegenerative disorders including Alzheimer’ s disease (AD). Generation of excessive amounts of aggregated proteins and impairment of degradation systems for misfolded proteins such as Autophagy can lead to accumulation of proteins in diseased neurons. Molecules that contribute to both these effects are emerging as critical players in disease pathogenesis. Furthermore, impairment of Autophagy under disease conditions can be both a cause and a consequence of abnormal protein accumulation. Specifically, disease-causing proteins can impair Autophagy, which further enhances the accumulation of abnormal proteins. In this short review, we focus on the relationship between the microtubule-associated protein Tau and Autophagy to highlight a feed-forward mechanism in disease pathogenesis.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    Samimi, Nastaran, Asada, Akiko, & Ando, Kanae. (2020). Tau Abnormalities and Autophagic Defects in Neurodegenerative Disorders; A Feed-forward Cycle (review article). GALEN MEDICAL JOURNAL, 9(1), 0-0. SID. https://sid.ir/paper/782924/en

    Vancouver: Copy

    Samimi Nastaran, Asada Akiko, Ando Kanae. Tau Abnormalities and Autophagic Defects in Neurodegenerative Disorders; A Feed-forward Cycle (review article). GALEN MEDICAL JOURNAL[Internet]. 2020;9(1):0-0. Available from: https://sid.ir/paper/782924/en

    IEEE: Copy

    Nastaran Samimi, Akiko Asada, and Kanae Ando, “Tau Abnormalities and Autophagic Defects in Neurodegenerative Disorders; A Feed-forward Cycle (review article),” GALEN MEDICAL JOURNAL, vol. 9, no. 1, pp. 0–0, 2020, [Online]. Available: https://sid.ir/paper/782924/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top