Effects of Medicinal Plants and Flavonoids on Parkinson’ s Disease: A Review on Basic and Clinical Evidences

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KHAZDAIR MOHAMMAD REZA; KIANMEHR MAJID; ANAEIGOUDARI AKBAR

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Advanced Pharmaceutical Bulletin Year:2021 | Volume:11 | Issue:2 Page(s): 224-232

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Title

Effects of Medicinal Plants and Flavonoids on Parkinson’ s Disease: A Review on Basic and Clinical Evidences

Author(s)

KHAZDAIR MOHAMMAD REZA | KIANMEHR MAJID | ANAEIGOUDARI AKBAR | Issue Writer Certificate

Keywords

Parkinson’s disease

Neurotoxicity

Medicinal plants

Flavonoids

Abstract

Parkinson’ s disease (PD) is a neurodegenerative disorder which is characterized by typical symptoms including gradual progressive muscle rigidity, tremor and loss of motor skills. Although there is no definitive cure for PD, the extract of some Medicinal plants and their ingredients have been suggested to relieve its symptoms and to prevent disability in patients. This review is focused on therapeutic effects of some Medicinal plants and their ingredients on PD. The findings presented in this review were collected from experimental and clinical studies in databases including PubMed, Web of Science and Google Scholar until the end of May 2019. The keywords “ Neurotoxicity “ or “ Parkinson’ s disease” or “ neuroprotective” and “ Medicinal plants” and “ Flavonoids” were searched. Based on the results of animal and clinical studies, the extract of Medicinal plants and their components which are discussed in this review have neuroprotective effects against PD. These protective properties mainly are mediated through inhibition of dopamine metabolizing enzymes, reduction oxidant markers, increase of antioxidant agents and suppression of neuro-inflammation.

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APA: Copy

KHAZDAIR, MOHAMMAD REZA, KIANMEHR, MAJID, & ANAEIGOUDARI, AKBAR. (2021). Effects of Medicinal Plants and Flavonoids on Parkinson’ s Disease: A Review on Basic and Clinical Evidences. ADVANCED PHARMACEUTICAL BULLETIN, 11(2), 224-232. SID. https://sid.ir/paper/783755/en

Vancouver: Copy

KHAZDAIR MOHAMMAD REZA, KIANMEHR MAJID, ANAEIGOUDARI AKBAR. Effects of Medicinal Plants and Flavonoids on Parkinson’ s Disease: A Review on Basic and Clinical Evidences. ADVANCED PHARMACEUTICAL BULLETIN[Internet]. 2021;11(2):224-232. Available from: https://sid.ir/paper/783755/en

IEEE: Copy

MOHAMMAD REZA KHAZDAIR, MAJID KIANMEHR, and AKBAR ANAEIGOUDARI, “Effects of Medicinal Plants and Flavonoids on Parkinson’ s Disease: A Review on Basic and Clinical Evidences,” ADVANCED PHARMACEUTICAL BULLETIN, vol. 11, no. 2, pp. 224–232, 2021, [Online]. Available: https://sid.ir/paper/783755/en

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