Prognostic Impact of Monocyte to Lymphocyte Ratio in Clinical Outcome of Patients with Hepatocellular Carcinoma: A Systematic Review and Meta-analysis

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Nouri Vaskeh Masoud; MIRZA AGHAZADEH ATTARI MOHAMMAD; Pashazadeh Fariba; AZAMI AGHDASH SABER; ALIZADEH HADI; Pouya Parnia; HALIMI MONIREH; Jadideslam Golamreza; ZAREI MOHAMMAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Galen Medical Journal Year:2020 | Volume:9 | Issue:1 Page(s): 0-0

Download Full-Text

View:

113

Download:

Cites:

Information Journal Paper

Title

Prognostic Impact of Monocyte to Lymphocyte Ratio in Clinical Outcome of Patients with Hepatocellular Carcinoma: A Systematic Review and Meta-analysis

Author(s)

Keywords

Hepatocellular Carcinoma

Liver Neoplasm

Lymphocyte to Monocyte Ratio

Survival

Disease-Free Survival

Abstract

Background: Lymphocyte to Monocyte Ratio (LMR) is a surrogate marker of systemic inflammation which is shown to be related to the patient’ s Survival in multiple malignancies. An important implication of this marker potentially is neoplasms in which there is no correlation between prognosis and histopathological staging and also has no reliable chemical markers associated with prognosis. Herein, this meta-analysis aimed to investigate the prognostic role of LMR in patients with Hepatocellular Carcinoma (HCC). Materials and Methods: In the current systemic review and meta-analysis, we conducted a systemic search of databases and indexing sources, including PubMed, EMBASE, Cochrane, Scopus, and ProQuest up to May 2019 toinclude studies on the prognostic significance of LMR on patients with HCC. Overall Survival (OS), disease-free Survival (DFS) and recurrence-free Survival (RFS) values were extracted from the studies and analyzed. The pooled hazard ratio with a 95% confidence interval was explored to identify the prognostic value of the LMR in the Survival of the patients with HCC. Results: A total of 12 studies with a total sample size of 3750 cases were included. There was significant heterogeneity among the studies; therefore, subgroup analysis was also performed. Overall analysis regarding OS showed an insignificant relationship between LMR and patient’ s prognosis, dividing to subgroups based on LMR cut-offs did not yield any significant result, subgroup analysis for RFS founded statistically significant results and LMR was significantly related to DFS. Conclusion: High LMR was associated with increased DFS and RFS, in return this association was not observed for OS.

Cites

No record.

References

Cite

APA: Copy

Nouri Vaskeh, Masoud, MIRZA AGHAZADEH ATTARI, MOHAMMAD, Pashazadeh, Fariba, AZAMI AGHDASH, SABER, ALIZADEH, HADI, Pouya, Parnia, HALIMI, MONIREH, Jadideslam, Golamreza, & ZAREI, MOHAMMAD. (2020). Prognostic Impact of Monocyte to Lymphocyte Ratio in Clinical Outcome of Patients with Hepatocellular Carcinoma: A Systematic Review and Meta-analysis. GALEN MEDICAL JOURNAL, 9(1), 0-0. SID. https://sid.ir/paper/784067/en

Vancouver: Copy

Nouri Vaskeh Masoud, MIRZA AGHAZADEH ATTARI MOHAMMAD, Pashazadeh Fariba, AZAMI AGHDASH SABER, ALIZADEH HADI, Pouya Parnia, HALIMI MONIREH, Jadideslam Golamreza, ZAREI MOHAMMAD. Prognostic Impact of Monocyte to Lymphocyte Ratio in Clinical Outcome of Patients with Hepatocellular Carcinoma: A Systematic Review and Meta-analysis. GALEN MEDICAL JOURNAL[Internet]. 2020;9(1):0-0. Available from: https://sid.ir/paper/784067/en

IEEE: Copy

Masoud Nouri Vaskeh, MOHAMMAD MIRZA AGHAZADEH ATTARI, Fariba Pashazadeh, SABER AZAMI AGHDASH, HADI ALIZADEH, Parnia Pouya, MONIREH HALIMI, Golamreza Jadideslam, and MOHAMMAD ZAREI, “Prognostic Impact of Monocyte to Lymphocyte Ratio in Clinical Outcome of Patients with Hepatocellular Carcinoma: A Systematic Review and Meta-analysis,” GALEN MEDICAL JOURNAL, vol. 9, no. 1, pp. 0–0, 2020, [Online]. Available: https://sid.ir/paper/784067/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops