IMMUNE THROMBOCYTOPENIC PURPURA AND RELEVANT FACTORS IN PATIENTS IN MOFID CHILDREN HOSPITAL FROM 2003 TO 2008

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ALAVI SAMIN; MALEK FATEMEH; EGHBALI AZIZ; ARZANIAN M.T.; SHAMSIAN SH.; AZARGASHB E.A.

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Journal: The Scientific Journal of Iranian Blood Transfusion Year:2009 | Volume:6 | Issue:3 (24) Page(s): 165-173

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Title

IMMUNE THROMBOCYTOPENIC PURPURA AND RELEVANT FACTORS IN PATIENTS IN MOFID CHILDREN HOSPITAL FROM 2003 TO 2008

Author(s)

Keywords

PURPURAQ3

THROMBOCYTOPENICQ3

IDIOPATHICQ3

CHILDQ2

BONE MARROWQ2

BLOOD PLATELETSQ2

Abstract

Background and Objectives: Immune THROMBOCYTOPENIC PURPURA is the most common cause of sudden onset of thrombocytopenia in a healthy CHILD. The object of the present study was to determine the demographic and clinical features, underlying factors which predict chronicity of disease, and quality status of BONE MARROW megakaryocytes of CHILDren with ITP.Materials and Methods: We conducted a 5-year retrospective study on CHILDren with a diagnosis of ITP in Mofid CHILDren Hospital from 2003 to 2008. Data were analysed by using SPSS software.Results: Forty seven point one and 52.9% of 153 patients with ITP were female and male, respectively. The mean age was 4.42±3.9 years (age range within 0.08-15 yrs). Among the patients, 70.8% had acute ITP and 29.2% chronic ITP. Distribution rates of petechiae and PURPURA over the patients' body were 54.9%, 32.7%, and 89.5% in head and neck, in trunk, and on extremities, respectively. There was a statistically significant correlation between age and epistaxis. In our study, 41.8% of patients had history of viral infection three weeks prior to presentation. The median platelet count was 19000/&l. A total of 147 cases underwent BONE MARROW aspiration in 61.2% of whom megakaryocyte count faced an increase, in 32% showed to be normal and in 6.8% on the contrary faced a decrease.Conclusions: In our study, no correlation was found either between megakaryocyte counts and acute or chronic ITP or between treatment response and chronicity. Insidious onset was the strongest predictor of chronic disease.

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APA: Copy

ALAVI, SAMIN, MALEK, FATEMEH, EGHBALI, AZIZ, ARZANIAN, M.T., SHAMSIAN, SH., & AZARGASHB, E.A.. (2009). IMMUNE THROMBOCYTOPENIC PURPURA AND RELEVANT FACTORS IN PATIENTS IN MOFID CHILDREN HOSPITAL FROM 2003 TO 2008. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), 6(3 (24)), 165-173. SID. https://sid.ir/paper/78439/en

Vancouver: Copy

ALAVI SAMIN, MALEK FATEMEH, EGHBALI AZIZ, ARZANIAN M.T., SHAMSIAN SH., AZARGASHB E.A.. IMMUNE THROMBOCYTOPENIC PURPURA AND RELEVANT FACTORS IN PATIENTS IN MOFID CHILDREN HOSPITAL FROM 2003 TO 2008. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON)[Internet]. 2009;6(3 (24)):165-173. Available from: https://sid.ir/paper/78439/en

IEEE: Copy

SAMIN ALAVI, FATEMEH MALEK, AZIZ EGHBALI, M.T. ARZANIAN, SH. SHAMSIAN, and E.A. AZARGASHB, “IMMUNE THROMBOCYTOPENIC PURPURA AND RELEVANT FACTORS IN PATIENTS IN MOFID CHILDREN HOSPITAL FROM 2003 TO 2008,” THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), vol. 6, no. 3 (24), pp. 165–173, 2009, [Online]. Available: https://sid.ir/paper/78439/en

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