Structural and Functional Analysis of Crucial Protein Complex in Basal Cell Skin Carcinoma via Network Construction

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ZAMANIAN AZODI MONA; REZAEI TAVIRANI MOSTAFA; REZAEI TAVIRANI MAJID; ROSTAMI NEJAD MOHAMMAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Galen Medical Journal Year:2018 | Volume:7 | Issue:1 Page(s): 0-0

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

Structural and Functional Analysis of Crucial Protein Complex in Basal Cell Skin Carcinoma via Network Construction

Author(s)

ZAMANIAN AZODI MONA | REZAEI TAVIRANI MOSTAFA | REZAEI TAVIRANI MAJID | ROSTAMI NEJAD MOHAMMAD | Issue Writer Certificate

Keywords

Protein Interaction Maps

Gene Ontology

Protein Complex

Skin Neoplasm

Abstract

Background: The basal-cell carcinoma (BCC) as one of the most common type of skin cancers reported to have an increasing trend during past years. Molecular approaches can be useful to advance diagnosis and treatment goals in this cancer. Materials and Methods: In this sense, one of the recent popular investigations, protein-protein interaction network analysis (PPI), was applied in this study to better facilitate molecular view of BCC. Cytoscape v3. 6. 0 and its plugins analyzed and explored the topological and annotation features of the constructed network. Result: Among TP53, EGFR, AKT1, ERBB2, HRAS, and CCND1 as central agents of the network, five of them were also present in the first prominent cluster of the network in which considered for further analysis. It is suggested that there are significant related biological processes, actions, and expression changes for this highlighted cluster that may be related to BCC risk. Conclusion: Therefore, the studied complex of proteins may worth considering for clinical studies and therapeutic interventions after validating by related tests. What is more, among these genes, EBBR2 has more to offer and consequently with additional values.

Cites

No record.

References

No record.

Cite

APA: Copy

ZAMANIAN AZODI, MONA, REZAEI TAVIRANI, MOSTAFA, REZAEI TAVIRANI, MAJID, & ROSTAMI NEJAD, MOHAMMAD. (2018). Structural and Functional Analysis of Crucial Protein Complex in Basal Cell Skin Carcinoma via Network Construction. GALEN MEDICAL JOURNAL, 7(1), 0-0. SID. https://sid.ir/paper/784629/en

Vancouver: Copy

ZAMANIAN AZODI MONA, REZAEI TAVIRANI MOSTAFA, REZAEI TAVIRANI MAJID, ROSTAMI NEJAD MOHAMMAD. Structural and Functional Analysis of Crucial Protein Complex in Basal Cell Skin Carcinoma via Network Construction. GALEN MEDICAL JOURNAL[Internet]. 2018;7(1):0-0. Available from: https://sid.ir/paper/784629/en

IEEE: Copy

MONA ZAMANIAN AZODI, MOSTAFA REZAEI TAVIRANI, MAJID REZAEI TAVIRANI, and MOHAMMAD ROSTAMI NEJAD, “Structural and Functional Analysis of Crucial Protein Complex in Basal Cell Skin Carcinoma via Network Construction,” GALEN MEDICAL JOURNAL, vol. 7, no. 1, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/784629/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops