HEMOGLOBIN Q-IRAN AND THE IMPORTANCE OF USING SUITABLE LABORATORY SCREENING METHODS-CASE REPORT

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KHATAMI SH.; ROUHI DEHNABEH S.; NAJMABADI H.

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Journal Paper

Paper Information

Journal: The Scientific Journal of Iranian Blood Transfusion Year:2014 | Volume:10 | Issue:4 (42) Page(s): 411-418

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Information Journal Paper

Title

HEMOGLOBIN Q-IRAN AND THE IMPORTANCE OF USING SUITABLE LABORATORY SCREENING METHODS-CASE REPORT

Author(s)

KHATAMI SH. | ROUHI DEHNABEH S. | NAJMABADI H. | Issue Writer Certificate

Keywords

HEMOGLOBIN QQ2

HEMOGLOBINOPATHIESQ3

SCREENINGQ2

IRANQ3

Abstract

Background and Objectives: Using suitable laboratory methods for the diagnosis of HEMOGLOBINOPATHIES in laboratories not equipped with automatic systems is essential. The correct diagnosis of HEMOGLOBIN Q-Iran (a75Asp ®His) is important.Case: A 33-year-old woman was referred to the national reference globin chain biosynthesis laboratory. The patient's globin chains chromatogram indicated an unknown peak after a globin chain peak. Direct conventional sequencing revealed single G to C missense mutation in the a-globin gene. The genetic analysis led to the identification of a rare hemoglobin variant.Conclusions: Medical diagnosis laboratories not equipped with modern automatic systems must run solubility test and hemoglobin electrophoresis on citrate agar and cellulose acetate for definite detection of Hb Q-Iran; otherwise, it can be regarded as a cause of misdiagnosis with hemoglobin S.

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APA: Copy

KHATAMI, SH., ROUHI DEHNABEH, S., & NAJMABADI, H.. (2014). HEMOGLOBIN Q-IRAN AND THE IMPORTANCE OF USING SUITABLE LABORATORY SCREENING METHODS-CASE REPORT. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), 10(4 (42)), 411-418. SID. https://sid.ir/paper/78587/en

Vancouver: Copy

KHATAMI SH., ROUHI DEHNABEH S., NAJMABADI H.. HEMOGLOBIN Q-IRAN AND THE IMPORTANCE OF USING SUITABLE LABORATORY SCREENING METHODS-CASE REPORT. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON)[Internet]. 2014;10(4 (42)):411-418. Available from: https://sid.ir/paper/78587/en

IEEE: Copy

SH. KHATAMI, S. ROUHI DEHNABEH, and H. NAJMABADI, “HEMOGLOBIN Q-IRAN AND THE IMPORTANCE OF USING SUITABLE LABORATORY SCREENING METHODS-CASE REPORT,” THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), vol. 10, no. 4 (42), pp. 411–418, 2014, [Online]. Available: https://sid.ir/paper/78587/en

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