PLATELET COMPATIBILITY ASSESSMENT BETWEEN AML PATIENTS AND PLATELET DONORS BY FLOW CYTOMETRY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SAYYADI M.; SHAIEGAN M.; NIKOUGOFTAR ZARIF M.; VAEZI M.; MALEK MOHAMMADI A.; AHMADI M.H.; MOHAMMADI S.; ZADSAR M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: The Scientific Journal of Iranian Blood Transfusion Year:2016 | Volume:13 | Issue:1 Page(s): 29-37

Download Full-Text

Persian Verion

View:

1,397

Download:

Cites:

Information Journal Paper

Title

PLATELET COMPATIBILITY ASSESSMENT BETWEEN AML PATIENTS AND PLATELET DONORS BY FLOW CYTOMETRY

Author(s)

Keywords

FLOW CYTOMETRYQ2

CROSSMATCHINGQ2

BLOODQ2

PLATELET-RICH PLASMAQ2

Abstract

Background and Objectives: One of the complications of repeated platelet transfusion is immune platelet refractoriness. In this study, a flow cytometic platelet cross-matching was performed to evaluate platelet transfusion outcome.Materials and Methods: In this descriptive study, fifteen patients with a history of multiple platelet transfusions and fifteen healthy participants as the control group were enrolled in this study. Platelet crossmatch was done and analyzed by the gate method. EDTA-anticoagulated BLOOD samples from healthy donors were collected and PRP sampls were obtained. The serum of each patient was added to platelet suspension and incubated with FITC-anti human IgG and was analyzed using a flow cytometer. Platelet cross-match results of the patients were compared with those of CCI.Results: Platelet cross match results were negatively correlated with 1-hour (r=-0.731, p=0.002) and 24-hour (r=-0.794, p=0.001) CCIs. There was a significant difference in the mean percentage of platelet crossmatch between the patients with immune platelet refractoriness (showing 1-hour CCIs less than 7500) and that of the control group and the patients without platelet refractoriness.Conclusions: The results showed that there was a significant correlation between platelet cross match by flowcytometry and 1-hour CCI results and this method could be applicable in the evaluation of platelet transfusion outcome.

Cites

No record.

References

No record.

Cite

APA: Copy

SAYYADI, M., SHAIEGAN, M., NIKOUGOFTAR ZARIF, M., VAEZI, M., MALEK MOHAMMADI, A., AHMADI, M.H., MOHAMMADI, S., & ZADSAR, M.. (2016). PLATELET COMPATIBILITY ASSESSMENT BETWEEN AML PATIENTS AND PLATELET DONORS BY FLOW CYTOMETRY. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), 13(1), 29-37. SID. https://sid.ir/paper/78775/en

Vancouver: Copy

SAYYADI M., SHAIEGAN M., NIKOUGOFTAR ZARIF M., VAEZI M., MALEK MOHAMMADI A., AHMADI M.H., MOHAMMADI S., ZADSAR M.. PLATELET COMPATIBILITY ASSESSMENT BETWEEN AML PATIENTS AND PLATELET DONORS BY FLOW CYTOMETRY. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON)[Internet]. 2016;13(1):29-37. Available from: https://sid.ir/paper/78775/en

IEEE: Copy

M. SAYYADI, M. SHAIEGAN, M. NIKOUGOFTAR ZARIF, M. VAEZI, A. MALEK MOHAMMADI, M.H. AHMADI, S. MOHAMMADI, and M. ZADSAR, “PLATELET COMPATIBILITY ASSESSMENT BETWEEN AML PATIENTS AND PLATELET DONORS BY FLOW CYTOMETRY,” THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), vol. 13, no. 1, pp. 29–37, 2016, [Online]. Available: https://sid.ir/paper/78775/en

Related Journal Papers