COMPARISON OF HYPERICIN CONTENT, ANTIOXIDANT, ANTIMICROBIAL AND CYTOTOXIC ACTIVITIES OF HYPERICUM PERFORATUM L. FROM THREE GEOGRAPHIC REGIONS OF IRAN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AKHBARI M.; EBRAHIMIAN M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Gorgan University of Medical Sciences Year:2017 | Volume:19 | Issue:1 (61) Page(s): 89-95

Download Full-Text

Persian Verion

View:

685

Download:

Cites:

Information Journal Paper

Title

COMPARISON OF HYPERICIN CONTENT, ANTIOXIDANT, ANTIMICROBIAL AND CYTOTOXIC ACTIVITIES OF HYPERICUM PERFORATUM L. FROM THREE GEOGRAPHIC REGIONS OF IRAN

Author(s)

AKHBARI M. | EBRAHIMIAN M. | Issue Writer Certificate

Keywords

HYPERICUM PERFORATUM L.Q1

HYPERICINQ1

ANTIOXIDANT ACTIVITYQ2

CYTOTOXIC ACTIVITYQ1

ANTIMICROBIAL ACTIVITYQ1

Abstract

Background and Objective: HYPERICIN is found in different species of Hypericum genus, as a main compound with antimicrobial, antiviral, nonspecific kinas inhibition and dopamin b-hydroxilase inhibitoring effects. This study was done to compare the HYPERICIN content, antioxidant, antimicrobial and cytotoxic activities of HYPERICUM PERFORATUM L. from three geographic regions of Iran.Methods: In this descriptive study, HYPERICIN content of aerial parts of H. perforatum L. was assessed using UV-Vis spectrometric method. ANTIOXIDANT ACTIVITY was measured using DPPH and b-carotene bleaching assay. Cytotoxicity was evaluated via brine shrimp lethality assay. ANTIMICROBIAL ACTIVITY was determined using inhibition zone diameter evaluation via disc diffusion method and measuring minimum inhibitory concentration (MIC) value.Results: HYPERICIN content of aerial parts of H. perforatum L. from Qom, Golestan and Kurdestan provinces were 673, 1223 and 1568 ppm, respectively. Antioxidant and cytotoxic activities in samples from Kurdestan was more than samples from Qom and Golestan. ANTIMICROBIAL ACTIVITY, as far as the number of sensitive microorganisms was evaluated. In this way the order of Golestan>Kurdestan>Qom was exhibited, however the extract of the plant from Kurdestan had the highest activity for two staphylococcus species with the inhibition zone diameter of 17 and 19 mm for S. aureus and S.epidermidis, respectively and MIC value of 250 mg/mL.Conclusion: HYPERICIN content was more from samples of Kurdistan province with cold climate. Antimicrobial, antioxidant and cytotoxic activities of aerial parts of all samples were high. There is a relationship between HYPERICIN content of aerial parts of H. perforatum L. and biological activities.

Cites

No record.

References

No record.

Cite

APA: Copy

AKHBARI, M., & EBRAHIMIAN, M.. (2017). COMPARISON OF HYPERICIN CONTENT, ANTIOXIDANT, ANTIMICROBIAL AND CYTOTOXIC ACTIVITIES OF HYPERICUM PERFORATUM L. FROM THREE GEOGRAPHIC REGIONS OF IRAN. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 19(1 (61) ), 89-95. SID. https://sid.ir/paper/79398/en

Vancouver: Copy

AKHBARI M., EBRAHIMIAN M.. COMPARISON OF HYPERICIN CONTENT, ANTIOXIDANT, ANTIMICROBIAL AND CYTOTOXIC ACTIVITIES OF HYPERICUM PERFORATUM L. FROM THREE GEOGRAPHIC REGIONS OF IRAN. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2017;19(1 (61) ):89-95. Available from: https://sid.ir/paper/79398/en

IEEE: Copy

M. AKHBARI, and M. EBRAHIMIAN, “COMPARISON OF HYPERICIN CONTENT, ANTIOXIDANT, ANTIMICROBIAL AND CYTOTOXIC ACTIVITIES OF HYPERICUM PERFORATUM L. FROM THREE GEOGRAPHIC REGIONS OF IRAN,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 19, no. 1 (61) , pp. 89–95, 2017, [Online]. Available: https://sid.ir/paper/79398/en

Related Journal Papers