NK, T AND B LYMPHOCYTE POPULATIONS IN INFERTILE WOMEN

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GHAFOURIAN BROOUJERDNIA M.; ESMAIELVANDI K.; SAFFARFAR V.; SAADATI N.

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Journal: JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES Year:2011 | Volume:13 | Issue:1 (37) Page(s): 51-58

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Information Journal Paper

Title

NK, T AND B LYMPHOCYTE POPULATIONS IN INFERTILE WOMEN

Author(s)

GHAFOURIAN BROOUJERDNIA M. | ESMAIELVANDI K. | SAFFARFAR V. | SAADATI N. | Issue Writer Certificate

Keywords

INFERTILITYQ2

T LYMPHOCYTESQ3

NK CELLSQ3

B CELLSQ3

FLOWCYTOMETRYQ3

Abstract

Background and Objective: Many different factors and problems can cause INFERTILITY. This study carried out to compare NK, T and B lymphocyte populations in peripheral blood of fertile and infertile women.Materials and Methods: In this case - control study 30 infertile women and 15 non pregnant women participated. The non pregnant women had a history of at least two alive children as a control group. The monoclonal antibodies and FLOWCYTOMETRY were used for evaluation of T cell subpopulations (CD3, CD4, CD8), B CELLS (CD22) and NK CELLS (CD56) in fertile and infertile women.Results: NK CELLS (CD56) significantly increased in infertile women compared with control groups (P=0.009) and T LYMPHOCYTES CD3, CD4 significantly reduced in infertile women compared with fertile women (P=0.013, P=0.004, respectively). CD4/CD8 ratio reduced in infertile women compared with fertile women (P=0.05). There was no difference in B CELLS and CD8 T cells in infertile women compared with controls.Conclusion: This study showed that NK CELLS increase and CD4 T LYMPHOCYTES reduce in infertile women. Our results suggest the immunological alterations may be related to INFERTILITY.

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APA: Copy

GHAFOURIAN BROOUJERDNIA, M., ESMAIELVANDI, K., SAFFARFAR, V., & SAADATI, N.. (2011). NK, T AND B LYMPHOCYTE POPULATIONS IN INFERTILE WOMEN. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 13(1 (37)), 51-58. SID. https://sid.ir/paper/79717/en

Vancouver: Copy

GHAFOURIAN BROOUJERDNIA M., ESMAIELVANDI K., SAFFARFAR V., SAADATI N.. NK, T AND B LYMPHOCYTE POPULATIONS IN INFERTILE WOMEN. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2011;13(1 (37)):51-58. Available from: https://sid.ir/paper/79717/en

IEEE: Copy

M. GHAFOURIAN BROOUJERDNIA, K. ESMAIELVANDI, V. SAFFARFAR, and N. SAADATI, “NK, T AND B LYMPHOCYTE POPULATIONS IN INFERTILE WOMEN,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 13, no. 1 (37), pp. 51–58, 2011, [Online]. Available: https://sid.ir/paper/79717/en

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