THE ANTIVIRAL EFFECT OF THREE PLANT SPECIES OF IRAN ON HSV-1

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FARAHANI MALIHE

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Journal: Yafteh Year:2016 | Volume:18 | Issue:1 (67) Page(s): 113-121

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Information Journal Paper

Title

THE ANTIVIRAL EFFECT OF THREE PLANT SPECIES OF IRAN ON HSV-1

Author(s)

FARAHANI MALIHE | Issue Writer Certificate

Keywords

INHIBITION EFFECTQ1

ANTIVIRAL EFFECTQ1

HSVQ2

1Q2

Abstract

Background: plants have had special position in human life and their medicinal application have been observed in manuscripts of many world scientists. Nowadays the treatment of HSV-1 infections with the available chemical drugs often leads to the problems due to viral resistance and virus latency duration, therefore there is a requirement for new anti-herpes drugs. In this research the ANTIVIRAL EFFECTs of Camellia sinesis, Echium amoenumL and Nerium oleander, with ethnomedical background on HSV-1 were studied.Materials and Methods: The plants were extracted with decoction method to obtain aqueous extracts and after evaluating their cytotoxicity on Hep-2 cell lines by evaluating CPE, antiherpes effect of the plants extracts were determined by cytopathic effect inhibition assay.Results: Nerium oleander extract had the most toxicity (> 50 mg/ml) on cell line and Camellia sinesis showed the most inhibitory property on HSV-1 multiplication. Echium amoenumL had the lowest antiherpes effect. Camellia sinesis was inhibitor of virus multiplication completely at 50-1000 mg/ml and Echium amoenumL at concentrations >300 mg/ml.Conclusion: Camellia sinesis and Echium amoenumL could inhibit well HSV-1 multiplication completely at concentrations nontoxic. Further researches are needed to find the effect mechanism of these drugs which may be used in the manufacture of new antiherpes drugs.

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APA: Copy

FARAHANI, MALIHE. (2016). THE ANTIVIRAL EFFECT OF THREE PLANT SPECIES OF IRAN ON HSV-1. YAFTEH, 18(1 (67)), 113-121. SID. https://sid.ir/paper/79989/en

Vancouver: Copy

FARAHANI MALIHE. THE ANTIVIRAL EFFECT OF THREE PLANT SPECIES OF IRAN ON HSV-1. YAFTEH[Internet]. 2016;18(1 (67)):113-121. Available from: https://sid.ir/paper/79989/en

IEEE: Copy

MALIHE FARAHANI, “THE ANTIVIRAL EFFECT OF THREE PLANT SPECIES OF IRAN ON HSV-1,” YAFTEH, vol. 18, no. 1 (67), pp. 113–121, 2016, [Online]. Available: https://sid.ir/paper/79989/en

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