EFFECT OF ATP-MGCI2-HYPERTONIC SOLUTION (HACI5%) ADMINISTRATION ON HEMORRHAGIC SHOCK

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NAZARI A.; FARAAHANI H.

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Journal: Yafteh Year:2004 | Volume:5 | Issue:17 Page(s): 25-30

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Title

EFFECT OF ATP-MGCI2-HYPERTONIC SOLUTION (HACI5%) ADMINISTRATION ON HEMORRHAGIC SHOCK

Author(s)

NAZARI A. | FARAAHANI H. | Issue Writer Certificate

Keywords

HEMORRHAGIC SHOCKQ4

HYPERTONIC AND ATP-MGCL2Q4

Abstract

Introduction: In the recent years, effect of hypertonic solution in resuscitation of shock has been shown by clinical and laboratory studies. On the other hand ATP-MgCI2 is used for better tissue perfusion and cardiac output in shock. The aim of this study is evaluation of ATP-MgCI2 with hypertonic solution in resuscitation of HEMORRHAGIC SHOCK.Materials and Methods: In this experimental study 21 rats were divided into three groups. After anaesthesia, induced HEMORRHAGIC SHOCK with bleeding and shock was for 30 minutes then the solutions were infused. Group I received hypertonic solution NaCl 5%, group2 ATP-MgCI2 and group3 both solutions and then systolic, diastolic, mean arterial blood pressure, serum electrolytes (Na+, K+), serum albumin, protein, and serum and urine osmolality before, and after one hour of shock were measured.Findings: Results showed that systolic BP in the first 15 minutes after resuscitation in group 1 and 3 was greater than group 2 (p<0.05) and between groups 1 and 3, group3 that received both solutions, showed greater elevation in systolic BP but it was not significant .60 minutes after resuscitation, mean arterial pressure in group I showed significant increase than other groups. Increasing in Na+ concentration in groups I and 3 had significant differences than group2. Albumin concentration in-group 2 was significantly greater than the other groups. There was no significant difference in other factors.Conclusion: It seems that ATP-MgCI2 alone or with hypertonic solution have no additional beneficial effect, than hypertonic solution, on hemodynamic and laboratory parameters in HEMORRHAGIC SHOCK.

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APA: Copy

NAZARI, A., & FARAAHANI, H.. (2004). EFFECT OF ATP-MGCI2-HYPERTONIC SOLUTION (HACI5%) ADMINISTRATION ON HEMORRHAGIC SHOCK. YAFTEH, 5(17), 25-30. SID. https://sid.ir/paper/80252/en

Vancouver: Copy

NAZARI A., FARAAHANI H.. EFFECT OF ATP-MGCI2-HYPERTONIC SOLUTION (HACI5%) ADMINISTRATION ON HEMORRHAGIC SHOCK. YAFTEH[Internet]. 2004;5(17):25-30. Available from: https://sid.ir/paper/80252/en

IEEE: Copy

A. NAZARI, and H. FARAAHANI, “EFFECT OF ATP-MGCI2-HYPERTONIC SOLUTION (HACI5%) ADMINISTRATION ON HEMORRHAGIC SHOCK,” YAFTEH, vol. 5, no. 17, pp. 25–30, 2004, [Online]. Available: https://sid.ir/paper/80252/en

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