THE IDENTIFICATION OF GENE CODING CYCLOTIDE FROM VIOLA SPECIES AND INVESTIGATION OF ANTIMICROBIAL ACTIVITIES OF EXTRACTED CYCLOTIDES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ZARABI MAHBOUBE; ROSHAN AKRAM; ASGARANI EZAT; PAKDEL MONA; ROUINI MAHSA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Sabzevar University of Medical Sciences Year:2017 | Volume:24 | Issue:2 Page(s): 89-96

Download Full-Text

Persian Verion

View:

1,599

Download:

Cites:

Information Journal Paper

Title

THE IDENTIFICATION OF GENE CODING CYCLOTIDE FROM VIOLA SPECIES AND INVESTIGATION OF ANTIMICROBIAL ACTIVITIES OF EXTRACTED CYCLOTIDES

Author(s)

Keywords

ANTIMICROBIALQ2

CYCLOTIDESQ1

VIOLAQ1

Abstract

Background and aim: CYCLOTIDES are plant polypeptides characterized by their unique cyclic cysteine knot structural motif. They are present in many plants from the VIOLAceae, Rubiaceae and Cucurbitaceae families. But they also have variety of biological activities, including anti-HIV, ANTIMICROBIAL and cytotoxic activities. Because of their exceptional stability, they have attracted interest as a potential starting point material for protein engineering and drug design.Materials and Methods: The aim of this study is identification of genes encoding CYCLOTIDES from V. odorata, V. occulta, and V. ignobilis. We also study ANTIMICROBIAL effect of CYCLOTIDES extracted from V. ignobilis. To reach this aim extraction of cyclotide was done by fractionation and solid phase extraction methods.Results: Findings indicate the presence of the cyclotide gene in all three plant species which studied. Examination of ANTIMICROBIAL effect of partial purified cyclotide, defined S. aureus is the most susceptible bacterium among human pathogenic and X. oryzea is the most susceptible bacterium among all of studied bacteria.Conclusion: In general, it seems that it can be used cyclotide peptide in most of the VIOLA species because of their anti-peptide property in the pharmaceutical industry. Study of cyclotide sequences shows that despite of existence of conserved amino acids in the most of CYCLOTIDES, the differences in performance are due to sequence variation.

Cites

The histomorphological effect of Viola odorata flower extract on skin wound healing process in Wistar rats

References

No record.

Cite

APA: Copy

ZARABI, MAHBOUBE, ROSHAN, AKRAM, ASGARANI, EZAT, PAKDEL, MONA, & ROUINI, MAHSA. (2017). THE IDENTIFICATION OF GENE CODING CYCLOTIDE FROM VIOLA SPECIES AND INVESTIGATION OF ANTIMICROBIAL ACTIVITIES OF EXTRACTED CYCLOTIDES. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 24(2), 89-96. SID. https://sid.ir/paper/81892/en

Vancouver: Copy

ZARABI MAHBOUBE, ROSHAN AKRAM, ASGARANI EZAT, PAKDEL MONA, ROUINI MAHSA. THE IDENTIFICATION OF GENE CODING CYCLOTIDE FROM VIOLA SPECIES AND INVESTIGATION OF ANTIMICROBIAL ACTIVITIES OF EXTRACTED CYCLOTIDES. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2017;24(2):89-96. Available from: https://sid.ir/paper/81892/en

IEEE: Copy

MAHBOUBE ZARABI, AKRAM ROSHAN, EZAT ASGARANI, MONA PAKDEL, and MAHSA ROUINI, “THE IDENTIFICATION OF GENE CODING CYCLOTIDE FROM VIOLA SPECIES AND INVESTIGATION OF ANTIMICROBIAL ACTIVITIES OF EXTRACTED CYCLOTIDES,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 2, pp. 89–96, 2017, [Online]. Available: https://sid.ir/paper/81892/en

Related Journal Papers