CHANGES IN PLASMA LEVELS AND EXPRESSION OF NEUROTROPHIN-3 GENE IN MULTIPLE SCLEROSIS PATIENTS FOLLOWING 8-WEEKS AQUATIC AND RESISTANCE EXERCISE TRAINING

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ASKARI ASRA; RASHIDLAMIR AMIR; BIJEH NAHID; MOMENI MOGHADDAM MOHAMMAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Sabzevar University of Medical Sciences Year:2018 | Volume:25 | Issue:3 Page(s): 451-460

Download Full-Text

Persian Verion

View:

827

Download:

Cites:

Information Journal Paper

Title

CHANGES IN PLASMA LEVELS AND EXPRESSION OF NEUROTROPHIN-3 GENE IN MULTIPLE SCLEROSIS PATIENTS FOLLOWING 8-WEEKS AQUATIC AND RESISTANCE EXERCISE TRAINING

Author(s)

ASKARI ASRA | RASHIDLAMIR AMIR | BIJEH NAHID | MOMENI MOGHADDAM MOHAMMAD | Issue Writer Certificate

Keywords

AQUATIC EXERCISEQ1

MULTIPLE SCLEROSISQ1

NEUROTROPHIN- 3Q1

RESISTANCE TRAININGQ1

Abstract

Background: Neurotrophin-3 is among the biomarkers studied in MS. Regarding the fact that exercise training has been proposed as an effective non-drug way of treating MULTIPLE SCLEROSIS (MS), the present study aims at investigating the effect of eight weeks’ AQUATIC EXERCISE and RESISTANCE TRAINING programs on the plasmatic levels and gene expression of neurotrophin-3 in MULTIPLE SCLEROSIS patients.Materials and Methods To the aims of the present study, 30 women with MS were randomly selected and assigned to three groups: the control group, RESISTANCE TRAINING group, and AQUATIC EXERCISE group. RESISTANCE TRAINING and AQUATIC EXERCISE programs were used for eight weeks. The control group did not receive any training. After separating plasma and PBMN cells, plasmatic levels and the expression of neurotrophin-3 gene were measured via ELISA and real-time PCR, respectively. In order to compare the means, plasmatic levels and the gene expression of neurotrophin-3 of the three groups were analyzed by the ANCOVA test at the significance level of p£0.05 through SPSS 18.Results The results showed a significant increase in plasma levels neurotrophin-3 of the three groups (p=0.001). The Scheffe post hoc test was significant in two by two comparisons of the aquatic group and RESISTANCE TRAINING group with the control group (p=0.001, p=0.001, respectively). However, the difference between the aquatic and resistance groups was not significant (p=0.329). Moreover, there was a significant increase in the gene expression of neurotrophin-3 of the three groups (p=0.001). Based on the Scheffe test, the mean differences between the aquatic and resistance groups, and the control group were p=0.053, p=0.001, respectively. However, non-significant differences in the gene expression of neurotrophin-3 were shown between the aquatic group and the resistance group (p=0.08).Conclusion The findings of the present study indicated that both the RESISTANCE TRAINING and the AQUATIC EXERCISE can increase plasmatic levels and the gene expression of neurotrophin-3 in PBMN cells in the women with MS..

Cites

No record.

References

No record.

Cite

APA: Copy

ASKARI, ASRA, RASHIDLAMIR, AMIR, BIJEH, NAHID, & MOMENI MOGHADDAM, MOHAMMAD. (2018). CHANGES IN PLASMA LEVELS AND EXPRESSION OF NEUROTROPHIN-3 GENE IN MULTIPLE SCLEROSIS PATIENTS FOLLOWING 8-WEEKS AQUATIC AND RESISTANCE EXERCISE TRAINING. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 25(3 ), 451-460. SID. https://sid.ir/paper/81916/en

Vancouver: Copy

ASKARI ASRA, RASHIDLAMIR AMIR, BIJEH NAHID, MOMENI MOGHADDAM MOHAMMAD. CHANGES IN PLASMA LEVELS AND EXPRESSION OF NEUROTROPHIN-3 GENE IN MULTIPLE SCLEROSIS PATIENTS FOLLOWING 8-WEEKS AQUATIC AND RESISTANCE EXERCISE TRAINING. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;25(3 ):451-460. Available from: https://sid.ir/paper/81916/en

IEEE: Copy

ASRA ASKARI, AMIR RASHIDLAMIR, NAHID BIJEH, and MOHAMMAD MOMENI MOGHADDAM, “CHANGES IN PLASMA LEVELS AND EXPRESSION OF NEUROTROPHIN-3 GENE IN MULTIPLE SCLEROSIS PATIENTS FOLLOWING 8-WEEKS AQUATIC AND RESISTANCE EXERCISE TRAINING,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 25, no. 3 , pp. 451–460, 2018, [Online]. Available: https://sid.ir/paper/81916/en

Related Journal Papers