COMPARISON OF EXTERNAL DCR SURGERY WITH AND WITHOUT INTRAOPERATIVE MITOMYCIN-C APPLICATION

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SAMAVATI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Paper Information

Journal: Journal of Sabzevar University of Medical Sciences Year:2005 | Volume:12 | Issue:1 (35) Page(s): 6-10

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Title

COMPARISON OF EXTERNAL DCR SURGERY WITH AND WITHOUT INTRAOPERATIVE MITOMYCIN-C APPLICATION

Author(s)

SAMAVATI M. | Issue Writer Certificate

Keywords

NASOLACRIMAL DUCT OBSTRUCTIONQ3

SURGERYQ2

MITOMYCIN-CQ3

OCRQ3

Abstract

Background and Purpose: This study is intended to evaluate the results of intraoperative Mitomycin- C application in external D.C.R SURGERY compared with same results without MITOMYCIN-C application.Methods and Materials: In this prospective randomized controlled study, a total of 66 eyes diagnosed with acquired NASOLACRIMAL DUCT OBSTRUCTION were randomly divided into a simple external D.C.R group and a MITOMYCIN-C group in which MITOMYCIN-C was used during SURGERY. The surgical procedures in both groups were exactly the same, except that in MITOMYCIN-C group, a piece of cotton soaked with 0.2 mg/ml MITOMYCIN-C was applied to osteotomy site for 20 minutes. The symptoms and signs of the two groups in a 7-month follow-up were evaluated.Results: In the simple D.C.R group, 75.8% of the patients remained Epiphora free after 7 months of follow-up; while in the MITOMYCIN-C group, 94% of patients were reported to be Epiphora-free. There was a significant difference between the two groups: the potency rate in simple group in 72.7% compared with 94% in the MITOMYCIN-C group. In the simple group, 69.7% having a normal tear Meniscus level compared with 91% in MITOMYCIN-C group. There were no severe complications except for one patient with delayed epistaxies and two patients with delayed wound healing in MITOMYCIN-C group.Conclusion: Intraoperative MITOMYCIN-C application is effective in increasing the success rate of D.C.R SURGERY and no significant complication results from its use.

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APA: Copy

SAMAVATI, M.. (2005). COMPARISON OF EXTERNAL DCR SURGERY WITH AND WITHOUT INTRAOPERATIVE MITOMYCIN-C APPLICATION. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 12(1 (35)), 6-10. SID. https://sid.ir/paper/82095/en

Vancouver: Copy

SAMAVATI M.. COMPARISON OF EXTERNAL DCR SURGERY WITH AND WITHOUT INTRAOPERATIVE MITOMYCIN-C APPLICATION. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2005;12(1 (35)):6-10. Available from: https://sid.ir/paper/82095/en

IEEE: Copy

M. SAMAVATI, “COMPARISON OF EXTERNAL DCR SURGERY WITH AND WITHOUT INTRAOPERATIVE MITOMYCIN-C APPLICATION,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 12, no. 1 (35), pp. 6–10, 2005, [Online]. Available: https://sid.ir/paper/82095/en

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