SEROEPIDEMIOLOGY OF ANTI-RUBELLA VIRUS IN PRE-MARRIAGE GIRLS OF SABZEVAR, IRAN BY ELISA METHOD

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SHIRZADEH E.; GOLMOHAMMADI R.; KHASHEEI R.

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Journal: Journal of Sabzevar University of Medical Sciences Year:2005 | Volume:12 | Issue:2 Page(s): 20-25

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Title

SEROEPIDEMIOLOGY OF ANTI-RUBELLA VIRUS IN PRE-MARRIAGE GIRLS OF SABZEVAR, IRAN BY ELISA METHOD

Author(s)

SHIRZADEH E. | GOLMOHAMMADI R. | KHASHEEI R. | Issue Writer Certificate

Keywords

RUBELLAQ3

ANTI-RUBELLAANTIBODYQ4

IGGQ2

IGMQ3

ELISAQ3

Abstract

Background and Purpose: RUBELLA is a member of togaviridate viruses, with minor morbidity in children. RUBELLA infection during pregnancy causes various malformations including congenital cataract. Immunity against it is, therefore, important in girls before marriage and it is recommended in girls without antiRUBELLA antibody in some countries. This study is intended to determine the anti-RUBELLA immunity in premarriage girls in Sabzevar, Iran.Methods and Materials: This descriptive-analytical study was conducted on 186 pre-marriage girls in Sabzevar, Iran to determine serological anti-RUBELLA (IgG and IGM)using ELlSA. NOVUM DIAGNOSTICA Kit was used for tests and SPSS for data analysis.Results: 172 girls (92.5%) were positive and 14 girls (7.5%) negative, Le. high risk group.152 girls (81.7%) already infected with RUBELLA were now positive and 11 girls (5.9%) negative.Conclusion: Subjects' age and IGG antibody did not show any significant relationships while a significant relationship was found between exposure to RUBELLA and IGG (p<0.0019); in otherwords,81.7%of the IGG positive cases were already exposed to RUBELLA and 5.9% of the cases with history of RUBELLA were IGG negative. Therefore, the high risk group is recommended to be vaccinated prior to pregnancy to prevent the risk of congenital RUBELLA syndrome.

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APA: Copy

SHIRZADEH, E., GOLMOHAMMADI, R., & KHASHEEI, R.. (2005). SEROEPIDEMIOLOGY OF ANTI-RUBELLA VIRUS IN PRE-MARRIAGE GIRLS OF SABZEVAR, IRAN BY ELISA METHOD. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 12(2), 20-25. SID. https://sid.ir/paper/82269/en

Vancouver: Copy

SHIRZADEH E., GOLMOHAMMADI R., KHASHEEI R.. SEROEPIDEMIOLOGY OF ANTI-RUBELLA VIRUS IN PRE-MARRIAGE GIRLS OF SABZEVAR, IRAN BY ELISA METHOD. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2005;12(2):20-25. Available from: https://sid.ir/paper/82269/en

IEEE: Copy

E. SHIRZADEH, R. GOLMOHAMMADI, and R. KHASHEEI, “SEROEPIDEMIOLOGY OF ANTI-RUBELLA VIRUS IN PRE-MARRIAGE GIRLS OF SABZEVAR, IRAN BY ELISA METHOD,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 12, no. 2, pp. 20–25, 2005, [Online]. Available: https://sid.ir/paper/82269/en

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