STUDY OF THE EFFECT OF METFORMIN ON THE PROFILE OF LIPIDS AND BODY WEIGHT IN TYPE II DIABETICS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AFKHAMI ARDEKANI MOHAMMAD; MOTAMEDZADEH A.R.; RASHIDI MARYAM

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Sabzevar University of Medical Sciences Year:2008 | Volume:14 | Issue:4 (46) Page(s): 205-210

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

6,442

Download:

Cites:

Information Journal Paper

Title

STUDY OF THE EFFECT OF METFORMIN ON THE PROFILE OF LIPIDS AND BODY WEIGHT IN TYPE II DIABETICS

Author(s)

AFKHAMI ARDEKANI MOHAMMAD | MOTAMEDZADEH A.R. | RASHIDI MARYAM | Issue Writer Certificate

Keywords

DIABETES MELLITUSQ3

FBSQ3

TRIGLYCERIDEQ3

CHOLESTEROLEQ3

METFORMINQ2

Abstract

Background and Purpose: Type II diabetes is a chronic disease characterized by insulin resistance, impaired insulin secretion and increased hepatic glucose production. METFORMIN is a biguanide which reduces the production of hepatic glucose and is able to increase the sensitivity of peripheral tissue to insulin. This study was designed to investigate the effect of METFORMIN on lipid profile and body weight.Methods and Materials: In this clinical trial, 51 type II diabetic patients, admitted to Yazd Research Crnter of Diabetes, with FBS>150 mg/dl, Tg>200 mg/dl and BMI>25 kg/m2 and no previous history of METFORMIN use, were selected. They were give METFORMIN for one month, 1 gr a day; after one month, they were assessed for BMI, 2hPP and FBS. Due to gastrointestinal complications, 4 patients were excluded from the research. Paired t-test was used in comparing the befor-after response means.Results: After using METFORMIN, CHOLESTEROLE and TRIGLYCERIDE dropped by 9.26±2.1 and 54.02±50.51 mg/dl respectively. Also, METFORMIN induced a significant decrease in FBS, 2h postprandial glucose and body weight. No significant relationship was observed between the mean weight loss and factors of age and sex.Conclusion: In the present study, METFORMIN reduced blood sugar, lipids and body weight.

Cites

EFFECTS OF “METFORMIN” ON SERUM GLUCOSE, LIPID PROFILES AND OXIDATIVE STRESS IN THE ALLOXAN-INDUCED DIABETIC RATS

References

No record.

Cite

APA: Copy

AFKHAMI ARDEKANI, MOHAMMAD, MOTAMEDZADEH, A.R., & RASHIDI, MARYAM. (2008). STUDY OF THE EFFECT OF METFORMIN ON THE PROFILE OF LIPIDS AND BODY WEIGHT IN TYPE II DIABETICS. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 14(4 (46)), 205-210. SID. https://sid.ir/paper/82481/en

Vancouver: Copy

AFKHAMI ARDEKANI MOHAMMAD, MOTAMEDZADEH A.R., RASHIDI MARYAM. STUDY OF THE EFFECT OF METFORMIN ON THE PROFILE OF LIPIDS AND BODY WEIGHT IN TYPE II DIABETICS. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2008;14(4 (46)):205-210. Available from: https://sid.ir/paper/82481/en

IEEE: Copy

MOHAMMAD AFKHAMI ARDEKANI, A.R. MOTAMEDZADEH, and MARYAM RASHIDI, “STUDY OF THE EFFECT OF METFORMIN ON THE PROFILE OF LIPIDS AND BODY WEIGHT IN TYPE II DIABETICS,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 14, no. 4 (46), pp. 205–210, 2008, [Online]. Available: https://sid.ir/paper/82481/en

Related Journal Papers