A comparative study on the effect of heparin on of intermittent intravenous injection and continuous infusion with syringe pump on APTT results and possible complications in patients with acute coronary syndrome

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Saneipour Ali; RAD MOJTABA; TABARAEI YASER; RAD MOSTAFA

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Journal: Journal of Sabzevar University of Medical Sciences Year:2019 | Volume:26 | Issue:3 Page(s): 373-381

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Information Journal Paper

Title

A comparative study on the effect of heparin on of intermittent intravenous injection and continuous infusion with syringe pump on APTT results and possible complications in patients with acute coronary syndrome

Author(s)

Saneipour Ali | RAD MOJTABA | TABARAEI YASER | RAD MOSTAFA | Issue Writer Certificate

Keywords

HeparinQ3

IntravenousQ2

InfusionQ2

Acute Coronary SyndromeQ2

Abstract

Background Ischemic heart disease is the first cause of early death in the world. One of the main treatments for patients with Acute Coronary Syndrome is the use of anticoagulants. The aim of this study, The aim of this study was to compare effect of two methods of intermittent Intravenous injection and continuous Infusion on APTT in patients with ACS. Materials and Methods clinical trial was performed on 60 patients selected by random sampling in Neishabour Hospital in 2018. To data gathering were used the demographic information questionnaire, and APTT checklist. The Intravenous injection group received 2500 units Heparin every 3 hours and Infusion group was given 1000 units per hour and APTT was controlled. Data analysis was done using SPSS-16 software and sinifiant level was considered to be less than 0. 05. Results Mean APTT level in first stage was 40. 8 ± 11. 17 and 38. 87 ± 8. 86 in intermittent Intravenous injection and continuous Infusion groups respectively. In the 8th stage, mean APTT level in Intravenous injection group was 55. 03 ± 8. 41 and in continuous Infusion group was 55. 7 ± 14. 09. Independent t-test did not show a significant difference between the two groups (P> 0. 05). Conclusion Regarding to approximation of the results in two methods, alternate injection method can be used instead of continuous Intravenous Infusion. This method creates less constraints for the patient and reduces the burden on nurses due to don’ t need setting pump syringe, serum Heparin preparation, and alleviation of alarms.

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References

Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970– 2016: a systematic analysis for the Global Burden of Disease Study 2016

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APA: Copy

Saneipour, Ali, RAD, MOJTABA, TABARAEI, YASER, & RAD, MOSTAFA. (2019). A comparative study on the effect of heparin on of intermittent intravenous injection and continuous infusion with syringe pump on APTT results and possible complications in patients with acute coronary syndrome. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 26(3 ), 373-381. SID. https://sid.ir/paper/82528/en

Vancouver: Copy

Saneipour Ali, RAD MOJTABA, TABARAEI YASER, RAD MOSTAFA. A comparative study on the effect of heparin on of intermittent intravenous injection and continuous infusion with syringe pump on APTT results and possible complications in patients with acute coronary syndrome. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;26(3 ):373-381. Available from: https://sid.ir/paper/82528/en

IEEE: Copy

Ali Saneipour, MOJTABA RAD, YASER TABARAEI, and MOSTAFA RAD, “A comparative study on the effect of heparin on of intermittent intravenous injection and continuous infusion with syringe pump on APTT results and possible complications in patients with acute coronary syndrome,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 26, no. 3 , pp. 373–381, 2019, [Online]. Available: https://sid.ir/paper/82528/en

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