THE EFFECT OF ALOE VERA EXTRACT ON CONCENTRATION CHANGES OF TESTOSTERONE AND GONADOTROPIN HORMONES IN ADULT MALE RAT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHARIATI MEHRDAD; MOKHTARI MOKHTAR; RASTGAR S.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Sabzevar University of Medical Sciences Year:2009 | Volume:16 | Issue:1 (51) Page(s): 12-17

Download Full-Text

Persian Verion

View:

4,913

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF ALOE VERA EXTRACT ON CONCENTRATION CHANGES OF TESTOSTERONE AND GONADOTROPIN HORMONES IN ADULT MALE RAT

Author(s)

SHARIATI MEHRDAD | MOKHTARI MOKHTAR | RASTGAR S. | Issue Writer Certificate

Keywords

Not Registered.

Abstract

Background and Purpose: While aloe vera has the capability of reducing libido, regulating menstruation, and being widely used, there is scarce information on the effect of its alcoholic extract on the functions of pituitary-gonad axis. Therefore, the present study aims at investigating the effect of Aloe vera alcoholic extract on spermatogenesis in male rat.Methods and Materials: In this experimental; study, 45 male Wistar rats were divided in to five groups including 1 control, 1 sham and three experimental groups. Each rat in the experimental groups was treated orally with 50, 100 and 150 (mg/kg) doses of Aloe vera alcoholic extract for twenty one days, after the extract was prepared via percolation. The sham group received distilled water and alcohol; while control rats received nothing. After twenty one days, blood samples were taken from each group directly from ventricles. Blood samples were used to measure the concentration changes of LH, FSH and testosterone hormones. Obtained data were statistically analyzed using Tukey test and LSD.Results: Concentrations of FSH in the average and maximum experimental groups (2.96±13.51 and 2.15±4.85 respectively) significantly reduced in comparison with the control group (3.11±2.16). also, concentrations of testosterone in the average and maximum experimental groups (6.18±3.41 and 3.92±5.27 respectively) significantly reduced in comparison with the control group (6.58±7.19). However, no significant changes were observed in the concentrations of LH across experimental and control groups.Conclusion: Based on the results, Aloe vera extract probably has anti-gonadotropin and antiandrogenic characteristics because of beta-sitosterol, ascorbic acid, P-coumaric acid, coumarin and aloe emodin. It can cause disorders in the secretion of gonadotropin hormone (FSH) and testosterone.

Cites

No record.

References

No record.

Cite

APA: Copy

SHARIATI, MEHRDAD, MOKHTARI, MOKHTAR, & RASTGAR, S.. (2009). THE EFFECT OF ALOE VERA EXTRACT ON CONCENTRATION CHANGES OF TESTOSTERONE AND GONADOTROPIN HORMONES IN ADULT MALE RAT. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 16(1 (51)), 12-17. SID. https://sid.ir/paper/82565/en

Vancouver: Copy

SHARIATI MEHRDAD, MOKHTARI MOKHTAR, RASTGAR S.. THE EFFECT OF ALOE VERA EXTRACT ON CONCENTRATION CHANGES OF TESTOSTERONE AND GONADOTROPIN HORMONES IN ADULT MALE RAT. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2009;16(1 (51)):12-17. Available from: https://sid.ir/paper/82565/en

IEEE: Copy

MEHRDAD SHARIATI, MOKHTAR MOKHTARI, and S. RASTGAR, “THE EFFECT OF ALOE VERA EXTRACT ON CONCENTRATION CHANGES OF TESTOSTERONE AND GONADOTROPIN HORMONES IN ADULT MALE RAT,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 16, no. 1 (51), pp. 12–17, 2009, [Online]. Available: https://sid.ir/paper/82565/en

Related Journal Papers