RELATIONSHIP BETWEEN PLASMA LEVELS OF ZINC AND LIPID OXIDIZABILITY IN DILUTED PLASMA

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JALALI KHANABADI B.A.; JAFARI AMENEH; MAHDAVI SEYED MAJID

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Journal: Zahedan Journal of Research in Medical Sciences Year:2007 | Volume:9 | Issue:1 Page(s): 11-18

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Title

RELATIONSHIP BETWEEN PLASMA LEVELS OF ZINC AND LIPID OXIDIZABILITY IN DILUTED PLASMA

Author(s)

JALALI KHANABADI B.A. | JAFARI AMENEH | MAHDAVI SEYED MAJID | Issue Writer Certificate

Keywords

PLASMAQ3

LIPIDSQ3

ZINCQ3

LIPID OXIDIZABILITYQ3

Abstract

Background: ZINC (Zn) is an essential trace element that has been regarded as having antioxidant properties. Some epidemiological studies have indicated the protective effect of Zn on lipid and lipoprotein peroxidation, but the underline mechanism is poorly understood. This study was conducted to evaluate the relationship between PLASMA Zn and copper-induced lipid peroxidation parameters in diluted PLASMA.Methods and Materials: In 100 healthy adult men (36.82±10.33 years), fasting PLASMA levels of Zn, LIPIDS, bilirubin, urate, malondialdehyde (MDA) and copper induced lipid peroxidation were evaluated. Lipid oxidation estimated by monitoring the change of conjugated dienes in 60-fold diluted PLASMA after addition of 60 I'M CU2+and MDA was determined by thiobarbituric acid method.Results: A significant correlation (r=0.24, p=0.024), between Lag-time (104±33 min) and PLASMA Zn levels (128.76±108.33 mg/dl) was found; however, no significant correlation was found between other parameters of lipid oxidation kinetics and MDA with PLASMA Zn levels. Conclusion: Based what the results indicated there is a delay in Cu-induced PLASMA lipid oxidation by higher levels of PLASMA Zn, but Zn level has no effect on finals oxidation products. It seems that Zn interferes with for Cu in the formation of an active oxidizing complex.

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APA: Copy

JALALI KHANABADI, B.A., JAFARI, AMENEH, & MAHDAVI, SEYED MAJID. (2007). RELATIONSHIP BETWEEN PLASMA LEVELS OF ZINC AND LIPID OXIDIZABILITY IN DILUTED PLASMA. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 9(1), 11-18. SID. https://sid.ir/paper/84280/en

Vancouver: Copy

JALALI KHANABADI B.A., JAFARI AMENEH, MAHDAVI SEYED MAJID. RELATIONSHIP BETWEEN PLASMA LEVELS OF ZINC AND LIPID OXIDIZABILITY IN DILUTED PLASMA. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)[Internet]. 2007;9(1):11-18. Available from: https://sid.ir/paper/84280/en

IEEE: Copy

B.A. JALALI KHANABADI, AMENEH JAFARI, and SEYED MAJID MAHDAVI, “RELATIONSHIP BETWEEN PLASMA LEVELS OF ZINC AND LIPID OXIDIZABILITY IN DILUTED PLASMA,” ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), vol. 9, no. 1, pp. 11–18, 2007, [Online]. Available: https://sid.ir/paper/84280/en

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