STUDY OF SOME BIOCHEMICAL AND HEMATOLOGICAL SERUM PARAMETERS IN SUSPICIOUS INTOXIFIED WORKERS WITH ZINC

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SAGHAEI F.; SAGHAEI L.A.; BADIEI A.

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Journal: Studies in Medical Sciences Year:2002 | Volume:13 | Issue:1 Page(s): 33-40

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Title

STUDY OF SOME BIOCHEMICAL AND HEMATOLOGICAL SERUM PARAMETERS IN SUSPICIOUS INTOXIFIED WORKERS WITH ZINC

Author(s)

SAGHAEI F. | SAGHAEI L.A. | BADIEI A. | Issue Writer Certificate

Keywords

ZINC TOXICITYQ4

IRONQ4

ZINC OXIDEQ2

COPPERQ3

Abstract

Introduction: Zinc is an essential trace element in human. Its major biochemical role being as constituent in a variety of metalloenzyme systems with catalytic functions. Zinc deficiency which causes lesions, alopecia and has linked to growth retardation and mental disturbance is relatively easily treated with zinc supplements. In contracts, serious exposure to ZINC OXIDE may cause ZINC TOXICITY. In this study, some biochemical and hematological serum parameters which are possibly resulted ZINC TOXICITY, were investigated. Materials & Methods: In this study blood samples of 18 normal inviduals and 18 workers which were exposed to ZnO for at least 10 years were collected and the concentration of zinc and COPPER were measured by atomic absorption. The coulter counter was used for determination of CBC, Hb and HCT. The amount of IRON, TIBC and the all types of lipids were also measured using different kits. Results: The results showed that the mean serum concentration of zinc in workers and healthy volunteers were 144 ±17 pg/dl and 114±15 pg/dl respectively. Serum levels of IRON, TIBC and Hb were reduced by 10.6, 12. 7 and 10.1percent compare to normal range respectively. These parameters were not significantly different in workers compare to healthy volunteers. Changes in COPPER and lipids were also not significantly different. Discussion: This study showed that in spite of elevation in serum zinc level in workers, other biochemical (serum COPPER, IRON and lipid protein) and hematological (Hb, hematocnit and CBC) parameters have not be affected which might be due to the duration for the toxicity.

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APA: Copy

SAGHAEI, F., SAGHAEI, L.A., & BADIEI, A.. (2002). STUDY OF SOME BIOCHEMICAL AND HEMATOLOGICAL SERUM PARAMETERS IN SUSPICIOUS INTOXIFIED WORKERS WITH ZINC. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 13(1), 33-40. SID. https://sid.ir/paper/63930/en

Vancouver: Copy

SAGHAEI F., SAGHAEI L.A., BADIEI A.. STUDY OF SOME BIOCHEMICAL AND HEMATOLOGICAL SERUM PARAMETERS IN SUSPICIOUS INTOXIFIED WORKERS WITH ZINC. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2002;13(1):33-40. Available from: https://sid.ir/paper/63930/en

IEEE: Copy

F. SAGHAEI, L.A. SAGHAEI, and A. BADIEI, “STUDY OF SOME BIOCHEMICAL AND HEMATOLOGICAL SERUM PARAMETERS IN SUSPICIOUS INTOXIFIED WORKERS WITH ZINC,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 13, no. 1, pp. 33–40, 2002, [Online]. Available: https://sid.ir/paper/63930/en

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